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Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS.
Masters AR, McCoy M, Jones DR, Desta Z. Masters AR, et al. Among authors: jones dr. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15;1015-1016:201-208. doi: 10.1016/j.jchromb.2016.02.018. Epub 2016 Feb 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 26946423 Free PMC article.
Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity.
Hertz DL, Deal A, Ibrahim JG, Walko CM, Weck KE, Anderson S, Magrinat G, Olajide O, Moore S, Raab R, Carrizosa DR, Corso S, Schwartz G, Graham M, Peppercorn JM, Jones DR, Desta Z, Flockhart DA, Evans JP, McLeod HL, Carey LA, Irvin WJ Jr. Hertz DL, et al. Among authors: jones dr. Oncologist. 2016 Jul;21(7):795-803. doi: 10.1634/theoncologist.2015-0480. Epub 2016 May 25. Oncologist. 2016. PMID: 27226358 Free PMC article.
In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles.
Hertz DL, Snavely AC, McLeod HL, Walko CM, Ibrahim JG, Anderson S, Weck KE, Magrinat G, Olajide O, Moore S, Raab R, Carrizosa DR, Corso S, Schwartz G, Peppercorn JM, Evans JP, Jones DR, Desta Z, Flockhart DA, Carey LA, Irvin WJ Jr. Hertz DL, et al. Among authors: jones dr. Br J Clin Pharmacol. 2015 Nov;80(5):1122-30. doi: 10.1111/bcp.12665. Epub 2015 Aug 2. Br J Clin Pharmacol. 2015. PMID: 25907378 Free PMC article. Clinical Trial.
1,392 results