Effect of coenzyme modification on the structural and catalytic properties of wild-type transketolase and of the variant E418A from Saccharomyces cerevisiae.
Golbik R, Meshalkina LE, Sandalova T, Tittmann K, Fiedler E, Neef H, König S, Kluger R, Kochetov GA, Schneider G, Hübner G.
Golbik R, et al. Among authors: schneider g.
FEBS J. 2005 Mar;272(6):1326-42. doi: 10.1111/j.1742-4658.2005.04562.x.
FEBS J. 2005.
PMID: 15752351
Free article.
In the E418A variant of transketolase reconstituted with N1'-methylated thiamin diphosphate, the electron density of the analogue was well defined and showed the typical V-conformation found in the wild-type holoenzyme [Lindqvist Y, Schneider G, Ermler U, Sundstrom …
In the E418A variant of transketolase reconstituted with N1'-methylated thiamin diphosphate, the electron density of the analogue was well d …