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One-year follow-up of direct myocardial gene transfer of vascular endothelial growth factor-2 using naked plasmid deoxyribonucleic acid by way of thoracotomy in no-option patients.
Fortuin FD, Vale P, Losordo DW, Symes J, DeLaria GA, Tyner JJ, Schaer GL, March R, Snell RJ, Henry TD, Van Camp J, Lopez JJ, Richenbacher W, Isner JM, Schatz RA. Fortuin FD, et al. Among authors: losordo dw. Am J Cardiol. 2003 Aug 15;92(4):436-9. doi: 10.1016/s0002-9149(03)00661-1. Am J Cardiol. 2003. PMID: 12914874 Clinical Trial.
The RENEW Trial: Efficacy and Safety of Intramyocardial Autologous CD34(+) Cell Administration in Patients With Refractory Angina.
Povsic TJ, Henry TD, Traverse JH, Fortuin FD, Schaer GL, Kereiakes DJ, Schatz RA, Zeiher AM, White CJ, Stewart DJ, Jolicoeur EM, Bass T, Henderson DA, Dignacco P, Gu Z, Al-Khalidi HR, Junge C, Nada A, Hunt AS, Losordo DW; RENEW Investigators. Povsic TJ, et al. Among authors: losordo dw. JACC Cardiovasc Interv. 2016 Aug 8;9(15):1576-85. doi: 10.1016/j.jcin.2016.05.003. JACC Cardiovasc Interv. 2016. PMID: 27491607 Free article. Clinical Trial.
Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials.
Henry TD, Losordo DW, Traverse JH, Schatz RA, Jolicoeur EM, Schaer GL, Clare R, Chiswell K, White CJ, Fortuin FD, Kereiakes DJ, Zeiher AM, Sherman W, Hunt AS, Povsic TJ. Henry TD, et al. Among authors: losordo dw. Eur Heart J. 2018 Jun 14;39(23):2208-2216. doi: 10.1093/eurheartj/ehx764. Eur Heart J. 2018. PMID: 29315376
Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia.
Losordo DW, Vale PR, Hendel RC, Milliken CE, Fortuin FD, Cummings N, Schatz RA, Asahara T, Isner JM, Kuntz RE. Losordo DW, et al. Circulation. 2002 Apr 30;105(17):2012-8. doi: 10.1161/01.cir.0000015982.70785.b7. Circulation. 2002. PMID: 11980678 Clinical Trial.
Gene therapy for myocardial angiogenesis.
Losordo DW, Vale PR, Isner JM. Losordo DW, et al. Am Heart J. 1999 Aug;138(2 Pt 2):S132-41. doi: 10.1016/s0002-8703(99)70333-9. Am Heart J. 1999. PMID: 10426872 Review.
240 results