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Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B-ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual disease.
Szczepański T, Willemse MJ, Brinkhof B, van Wering ER, van der Burg M, van Dongen JJ. Szczepański T, et al. Among authors: van dongen jj, van der burg m, van wering er. Blood. 2002 Apr 1;99(7):2315-23. doi: 10.1182/blood.v99.7.2315. Blood. 2002. PMID: 11895762 Free article.
Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias: alternative PCR targets for detection of minimal residual disease.
Szczepański T, Beishuizen A, Pongers-Willemse MJ, Hählen K, Van Wering ER, Wijkhuijs AJ, Tibbe GJ, De Bruijn MA, Van Dongen JJ. Szczepański T, et al. Among authors: van dongen jj, van wering er. Leukemia. 1999 Feb;13(2):196-205. doi: 10.1038/sj.leu.2401277. Leukemia. 1999. PMID: 10025893 Clinical Trial.
Ig heavy chain gene rearrangements in T-cell acute lymphoblastic leukemia exhibit predominant DH6-19 and DH7-27 gene usage, can result in complete V-D-J rearrangements, and are rare in T-cell receptor alpha beta lineage.
Szczepański T, Pongers-Willemse MJ, Langerak AW, Harts WA, Wijkhuijs AJ, van Wering ER, van Dongen JJ. Szczepański T, et al. Among authors: van dongen jj, van wering er. Blood. 1999 Jun 15;93(12):4079-85. Blood. 1999. PMID: 10361104 Free article.
T-lymphocytes in bone marrow samples of children with acute lymphoblastic leukemia during and after chemotherapy might hamper PCR-based minimal residual disease studies.
van Wering ER, van der Linden-Schrever BE, van der Velden VH, Szczepański T, van Dongen JJ. van Wering ER, et al. Among authors: van der velden vh, van der linden schrever be, van dongen jj. Leukemia. 2001 Aug;15(8):1301-3. doi: 10.1038/sj.leu.2402184. Leukemia. 2001. PMID: 11480575 No abstract available.
182 results