Inhibition of angiogenesis through modulation of collagen metabolism.
Ingber D, Folkman J.
Ingber D, et al.
Lab Invest. 1988 Jul;59(1):44-51.
Lab Invest. 1988.
PMID: 2455830
Regression of growing capillaries was induced by proline analogs (1-azetidine-2-carboxylic acid, cis-hydroxyproline,d,L-3,4-dehydroproline, thioproline) and an inhibitor of prolyl hydroxylase (alpha,alpha-dipyridyl) which interfere with triple helix formation and prevent c …
Regression of growing capillaries was induced by proline analogs (1-azetidine-2-carboxylic acid, cis-hydroxyproline,d,L-3,4-dehydropr …