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Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior.
Fitzsimons CP, van Hooijdonk LW, Schouten M, Zalachoras I, Brinks V, Zheng T, Schouten TG, Saaltink DJ, Dijkmans T, Steindler DA, Verhaagen J, Verbeek FJ, Lucassen PJ, de Kloet ER, Meijer OC, Karst H, Joels M, Oitzl MS, Vreugdenhil E. Fitzsimons CP, et al. Mol Psychiatry. 2013 Sep;18(9):993-1005. doi: 10.1038/mp.2012.123. Epub 2012 Aug 28. Mol Psychiatry. 2013. PMID: 22925833
Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model.
van Olst L, Verhaege D, Franssen M, Kamermans A, Roucourt B, Carmans S, Ytebrouck E, van der Pol SMA, Wever D, Popovic M, Vandenbroucke RE, Sobrino T, Schouten M, de Vries HE. van Olst L, et al. Neurobiol Aging. 2020 May;89:89-98. doi: 10.1016/j.neurobiolaging.2020.01.003. Epub 2020 Jan 10. Neurobiol Aging. 2020. PMID: 32008854 Free article.
Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain.
Schouten M, Bielefeld P, Garcia-Corzo L, Passchier EMJ, Gradari S, Jungenitz T, Pons-Espinal M, Gebara E, Martín-Suárez S, Lucassen PJ, De Vries HE, Trejo JL, Schwarzacher SW, De Pietri Tonelli D, Toni N, Mira H, Encinas JM, Fitzsimons CP. Schouten M, et al. Mol Psychiatry. 2020 Jul;25(7):1382-1405. doi: 10.1038/s41380-019-0440-2. Epub 2019 Jun 20. Mol Psychiatry. 2020. PMID: 31222184 Free PMC article.
Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease.
Fitzsimons CP, van Bodegraven E, Schouten M, Lardenoije R, Kompotis K, Kenis G, van den Hurk M, Boks MP, Biojone C, Joca S, Steinbusch HW, Lunnon K, Mastroeni DF, Mill J, Lucassen PJ, Coleman PD, van den Hove DL, Rutten BP. Fitzsimons CP, et al. Mol Neurodegener. 2014 Jun 25;9:25. doi: 10.1186/1750-1326-9-25. Mol Neurodegener. 2014. PMID: 24964731 Free PMC article. Review.
19 results