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Animal drug shortages limit veterinary therapeutic options and introduce artifacts in antimicrobial sales reporting.
Members of the AVMA Committee on Antimicrobials:; Robbins RC, Singer RS, Innes GK, Plummer PJ, Apley MD, Gaunt PS, Papich MG, Granick J, Marshall ES, Smith DR, Frey E, Cervantes HM, Beaudoin AL, Canon AJ, Brookshire C, Buckley M, Whaley J, Schnabel L, Costin M. Members of the AVMA Committee on Antimicrobials:, et al. Among authors: whaley j. J Am Vet Med Assoc. 2024 Jan 3;262(4):576-579. doi: 10.2460/javma.23.10.0603. Print 2024 Apr 1. J Am Vet Med Assoc. 2024. PMID: 38171090
Discovery of 12 (BMS-986172) as a Highly Potent MGAT2 Inhibitor that Achieved Targeted Efficacious Exposures at a Low Human Dose for the Treatment of Metabolic Disorders.
Meng W, Brigance R, Mignone J, Negash L, Zhao G, Ahmad S, Wang W, Moore F, Ye XY, Sun JH, Mathur A, Li YX, Azzara A, Ma Z, Chu CH, Cullen MJ, Rooney S, Harvey S, Kopcho L, Abell L, O'Malley K, Keim W, Dierks EA, Chang S, Foster KA, Harden D, Dabros M, Goti V, De Oliveira C, Krishna G, Pelleymounter MA, Whaley J, Robl JA, Cheng D, Devasthale P. Meng W, et al. Among authors: whaley j. J Med Chem. 2023 Sep 28;66(18):13135-13147. doi: 10.1021/acs.jmedchem.3c01147. Epub 2023 Sep 19. J Med Chem. 2023. PMID: 37724542
Patterned Adhesion Layer Enables Rugged Pd-MIS Hydrogen Sensors.
Hood R, Kolasinski RD, Zutter B, Friddle RW, Sugar JD, Bartelt NC, Habermehl S, Whaley JA, Talin AA. Hood R, et al. Among authors: whaley ja. ACS Appl Mater Interfaces. 2023 Sep 6;15(35):41598-41605. doi: 10.1021/acsami.3c04823. Epub 2023 Aug 22. ACS Appl Mater Interfaces. 2023. PMID: 37607333
Discovery of novel pyridinones as MGAT2 inhibitors for the treatment of metabolic disorders.
Moore F, Wang W, Zhao G, Mignone J, Meng W, Chu CH, Ma Z, Azzara A, Cullen MJ, Pelleymounter MA, Appiah K, Cvijic ME, Dierks E, Chang S, Foster K, Kopcho L, O'Malley K, Li YX, Khandelwal P, Whaley JM, Mathur A, Hou X, Wu DR, Robl JA, Cheng D, Devasthale P. Moore F, et al. Among authors: whaley jm. Bioorg Med Chem Lett. 2023 Jul 15;91:129362. doi: 10.1016/j.bmcl.2023.129362. Epub 2023 Jun 8. Bioorg Med Chem Lett. 2023. PMID: 37295614
Effect of Instrumented Spine Surgery on Length of Stay.
Lundgren ME, Detwiler AN, Lamping JW, Gael SL, Chen NW, Kasir R, Whaley JD, Park DK. Lundgren ME, et al. Among authors: whaley jd. J Am Acad Orthop Surg Glob Res Rev. 2023 May 15;7(5):e22.00231. doi: 10.5435/JAAOSGlobal-D-22-00231. eCollection 2023 May 1. J Am Acad Orthop Surg Glob Res Rev. 2023. PMID: 37186578 Free PMC article.
Optimization of physicochemical properties of pyrrolidine GPR40 AgoPAMs results in a differentiated profile with improved pharmacokinetics and reduced off-target activities.
Jurica EA, Wu X, Williams KN, Haque LE, Rampulla RA, Mathur A, Zhou M, Cao G, Cai H, Wang T, Liu H, Xu C, Kunselman LK, Antrilli TM, Hicks MB, Sun Q, Dierks EA, Apedo A, Moore DB, Foster KA, Cvijic ME, Panemangalore R, Khandelwal P, Wilkes JJ, Zinker BA, Robertson DG, Janovitz EB, Galella M, Li YX, Li J, Ramar T, Jalagam PR, Jayaram R, Whaley JM, Barrish JC, Robl JA, Ewing WR, Ellsworth BA. Jurica EA, et al. Among authors: whaley jm. Bioorg Med Chem. 2023 May 1;85:117273. doi: 10.1016/j.bmc.2023.117273. Epub 2023 Apr 4. Bioorg Med Chem. 2023. PMID: 37030194
Vertebral Augmentation in Spine Surgery.
Hoffmann J, Preston G, Whaley J, Khalil JG. Hoffmann J, et al. Among authors: whaley j. J Am Acad Orthop Surg. 2023 May 15;31(10):477-489. doi: 10.5435/JAAOS-D-22-00958. Epub 2023 Mar 23. J Am Acad Orthop Surg. 2023. PMID: 36952673 Review.
141 results