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Treatment of patients with chronic granulomatous disease with recombinant human interferon-gamma does not improve neutrophil oxidative metabolism, cytochrome b558 content or levels of four anti-microbial proteins.
Mühlebach TJ, Gabay J, Nathan CF, Erny C, Dopfer G, Schroten H, Wahn V, Seger RA. Mühlebach TJ, et al. Clin Exp Immunol. 1992 May;88(2):203-6. doi: 10.1111/j.1365-2249.1992.tb03062.x. Clin Exp Immunol. 1992. PMID: 1572085 Free PMC article. Clinical Trial.
Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.
Dinauer MC, Pierce EA, Erickson RW, Muhlebach TJ, Messner H, Orkin SH, Seger RA, Curnutte JT. Dinauer MC, et al. Among authors: muhlebach tj. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11231-5. doi: 10.1073/pnas.88.24.11231. Proc Natl Acad Sci U S A. 1991. PMID: 1763037 Free PMC article.
A second NsiI RFLP at the CYBB locus.
Mühlebach TJ, Robinson W, Seger RA, Mächler M. Mühlebach TJ, et al. Nucleic Acids Res. 1990 Aug 25;18(16):4966. doi: 10.1093/nar/18.16.4966-a. Nucleic Acids Res. 1990. PMID: 1975684 Free PMC article. No abstract available.