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Interrupting autocrine ligand-receptor binding: comparison between receptor blockers and ligand decoys.
Forsten KE, Lauffenburger DA. Forsten KE, et al. Among authors: lauffenburger da. Biophys J. 1992 Sep;63(3):857-61. doi: 10.1016/S0006-3495(92)81661-2. Biophys J. 1992. PMID: 1330038 Free PMC article.
Previous theoretical work using a compartmentalized model for autocrine cells has elucidated the conditions under which addition of solution decoys for the autocrine ligand can interrupt cell receptor/ligand binding via competitive binding of the secreted molecules (Forsten, K. E …
Previous theoretical work using a compartmentalized model for autocrine cells has elucidated the conditions under which addition of solution …
Receptor-mediated cell attachment and detachment kinetics. I. Probabilistic model and analysis.
Cozens-Roberts C, Lauffenburger DA, Quinn JA. Cozens-Roberts C, et al. Among authors: lauffenburger da. Biophys J. 1990 Oct;58(4):841-56. doi: 10.1016/S0006-3495(90)82430-9. Biophys J. 1990. PMID: 2174271 Free PMC article.
We present a probabilistic model of receptor-ligand bond formation between a cell and surface to describe the probability of adhesion in a fluid shear field. Our model extends the deterministic model of Hammer and Lauffenburger (Hammer, D.A., and D.A. Lauf …
We present a probabilistic model of receptor-ligand bond formation between a cell and surface to describe the probability of adhesion in a f …
Mathematical analysis of cell-target encounter rates in three dimensions. Effect of chemotaxis.
Charnick SB, Lauffenburger DA. Charnick SB, et al. Among authors: lauffenburger da. Biophys J. 1990 May;57(5):1009-23. doi: 10.1016/S0006-3495(90)82620-5. Biophys J. 1990. PMID: 2340340 Free PMC article.
These immune cells orient the direction of their motion in the presence of gradients in chemical attractants generated by pathogens. Fisher and Lauffenburger (1987. Biophys. J. 51:705-716) developed a model for macrophage/bacterium encounter in two dimensions which include …
These immune cells orient the direction of their motion in the presence of gradients in chemical attractants generated by pathogens. Fisher …
573 results