Pasparakis M - Search Results

1

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

Kanters E, Pasparakis M, Gijbels MJ, Vergouwe MN, Partouns-Hendriks I, Fijneman RJ, Clausen BE, Förster I, Kockx MM, Rajewsky K, Kraal G, Hofker MH, de Winther MP. Kanters E, et al. Among authors: pasparakis m. J Clin Invest. 2003 Oct;112(8):1176-85. doi: 10.1172/JCI18580. J Clin Invest. 2003. PMID: 14561702 Free PMC article.

2

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

Schmidt-Supprian M, Bloch W, Courtois G, Addicks K, Israël A, Rajewsky K, Pasparakis M. Schmidt-Supprian M, et al. Among authors: pasparakis m. Mol Cell. 2000 Jun;5(6):981-92. doi: 10.1016/s1097-2765(00)80263-4. Mol Cell. 2000. PMID: 10911992 Free article.

3

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2.

Pasparakis M, Courtois G, Hafner M, Schmidt-Supprian M, Nenci A, Toksoy A, Krampert M, Goebeler M, Gillitzer R, Israel A, Krieg T, Rajewsky K, Haase I. Pasparakis M, et al. Nature. 2002 Jun 20;417(6891):861-6. doi: 10.1038/nature00820. Nature. 2002. PMID: 12075355

4

IkappaB kinase signaling is essential for maintenance of mature B cells.

Pasparakis M, Schmidt-Supprian M, Rajewsky K. Pasparakis M, et al. J Exp Med. 2002 Sep 16;196(6):743-52. doi: 10.1084/jem.20020907. J Exp Med. 2002. PMID: 12235208 Free PMC article.

5

Mature T cells depend on signaling through the IKK complex.

Schmidt-Supprian M, Courtois G, Tian J, Coyle AJ, Israël A, Rajewsky K, Pasparakis M. Schmidt-Supprian M, et al. Among authors: pasparakis m. Immunity. 2003 Sep;19(3):377-89. doi: 10.1016/s1074-7613(03)00237-1. Immunity. 2003. PMID: 14499113 Free article.

6

Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance.

Röhl M, Pasparakis M, Baudler S, Baumgartl J, Gautam D, Huth M, De Lorenzi R, Krone W, Rajewsky K, Brüning JC. Röhl M, et al. Among authors: pasparakis m. J Clin Invest. 2004 Feb;113(3):474-81. doi: 10.1172/JCI18712. J Clin Invest. 2004. PMID: 14755344 Free PMC article.

7

Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation.

Schmidt-Supprian M, Tian J, Grant EP, Pasparakis M, Maehr R, Ovaa H, Ploegh HL, Coyle AJ, Rajewsky K. Schmidt-Supprian M, et al. Among authors: pasparakis m. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4566-71. doi: 10.1073/pnas.0400885101. Epub 2004 Mar 16. Proc Natl Acad Sci U S A. 2004. PMID: 15070758 Free PMC article.

8

I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion.

Schmidt-Supprian M, Tian J, Ji H, Terhorst C, Bhan AK, Grant EP, Pasparakis M, Casola S, Coyle AJ, Rajewsky K. Schmidt-Supprian M, et al. Among authors: pasparakis m. J Immunol. 2004 Aug 1;173(3):1612-9. doi: 10.4049/jimmunol.173.3.1612. J Immunol. 2004. PMID: 15265889

9

Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury.

Luedde T, Assmus U, Wüstefeld T, Meyer zu Vilsendorf A, Roskams T, Schmidt-Supprian M, Rajewsky K, Brenner DA, Manns MP, Pasparakis M, Trautwein C. Luedde T, et al. Among authors: pasparakis m. J Clin Invest. 2005 Apr;115(4):849-59. doi: 10.1172/JCI23493. Epub 2005 Mar 17. J Clin Invest. 2005. PMID: 15776110 Free PMC article.

10

Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling.

Nenci A, Huth M, Funteh A, Schmidt-Supprian M, Bloch W, Metzger D, Chambon P, Rajewsky K, Krieg T, Haase I, Pasparakis M. Nenci A, et al. Among authors: pasparakis m. Hum Mol Genet. 2006 Feb 15;15(4):531-42. doi: 10.1093/hmg/ddi470. Epub 2006 Jan 6. Hum Mol Genet. 2006. PMID: 16399796

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