Fyfe JC - Search Results

1

The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless.

Fyfe JC, Madsen M, Højrup P, Christensen EI, Tanner SM, de la Chapelle A, He Q, Moestrup SK. Fyfe JC, et al. Blood. 2004 Mar 1;103(5):1573-9. doi: 10.1182/blood-2003-08-2852. Epub 2003 Oct 23. Blood. 2004. PMID: 14576052 Free article.

2

Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo.

He Q, Madsen M, Kilkenney A, Gregory B, Christensen EI, Vorum H, Højrup P, Schäffer AA, Kirkness EF, Tanner SM, de la Chapelle A, Giger U, Moestrup SK, Fyfe JC. He Q, et al. Among authors: fyfe jc. Blood. 2005 Aug 15;106(4):1447-53. doi: 10.1182/blood-2005-03-1197. Epub 2005 Apr 21. Blood. 2005. PMID: 15845892 Free PMC article.

3

The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.

Kozyraki R, Fyfe J, Kristiansen M, Gerdes C, Jacobsen C, Cui S, Christensen EI, Aminoff M, de la Chapelle A, Krahe R, Verroust PJ, Moestrup SK. Kozyraki R, et al. Nat Med. 1999 Jun;5(6):656-61. doi: 10.1038/9504. Nat Med. 1999. PMID: 10371504

4

Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin.

Gburek J, Verroust PJ, Willnow TE, Fyfe JC, Nowacki W, Jacobsen C, Moestrup SK, Christensen EI. Gburek J, et al. Among authors: fyfe jc. J Am Soc Nephrol. 2002 Feb;13(2):423-430. doi: 10.1681/ASN.V132423. J Am Soc Nephrol. 2002. PMID: 11805171

5

Genetic evidence of an accessory activity required specifically for cubilin brush-border expression and intrinsic factor-cobalamin absorption.

Xu D, Kozyraki R, Newman TC, Fyfe JC. Xu D, et al. Among authors: fyfe jc. Blood. 1999 Nov 15;94(10):3604-6. Blood. 1999. PMID: 10552972 Free article.

6

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).

Nykjaer A, Fyfe JC, Kozyraki R, Leheste JR, Jacobsen C, Nielsen MS, Verroust PJ, Aminoff M, de la Chapelle A, Moestrup SK, Ray R, Gliemann J, Willnow TE, Christensen EI. Nykjaer A, et al. Among authors: fyfe jc. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13895-900. doi: 10.1073/pnas.241516998. Proc Natl Acad Sci U S A. 2001. PMID: 11717447 Free PMC article.

7

Cubilin is an albumin binding protein important for renal tubular albumin reabsorption.

Birn H, Fyfe JC, Jacobsen C, Mounier F, Verroust PJ, Orskov H, Willnow TE, Moestrup SK, Christensen EI. Birn H, et al. Among authors: fyfe jc. J Clin Invest. 2000 May;105(10):1353-61. doi: 10.1172/JCI8862. J Clin Invest. 2000. PMID: 10811843 Free PMC article.

8

Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia.

Kozyraki R, Fyfe J, Verroust PJ, Jacobsen C, Dautry-Varsat A, Gburek J, Willnow TE, Christensen EI, Moestrup SK. Kozyraki R, et al. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12491-6. doi: 10.1073/pnas.211291398. Epub 2001 Oct 16. Proc Natl Acad Sci U S A. 2001. PMID: 11606717 Free PMC article.

9

Canine Imerslund-Gräsbeck syndrome maps to a region orthologous to HSA14q.

He Q, Fyfe JC, Schäffer AA, Kilkenney A, Werner P, Kirkness EF, Henthorn PS. He Q, et al. Among authors: fyfe jc. Mamm Genome. 2003 Nov;14(11):758-64. doi: 10.1007/s00335-003-2280-1. Mamm Genome. 2003. PMID: 14722725

10

Inherited motor neuron disease in domestic cats: a model of spinal muscular atrophy.

He Q, Lowrie C, Shelton GD, Castellani RJ, Menotti-Raymond M, Murphy W, O'Brien SJ, Swanson WF, Fyfe JC. He Q, et al. Among authors: fyfe jc. Pediatr Res. 2005 Mar;57(3):324-30. doi: 10.1203/01.PDR.0000153625.46892.6F. Epub 2005 Jan 5. Pediatr Res. 2005. PMID: 15635053

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