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High avidity antigen-specific CTL identified by CD8-independent tetramer staining.
Choi EM, Chen JL, Wooldridge L, Salio M, Lissina A, Lissin N, Hermans IF, Silk JD, Mirza F, Palmowski MJ, Dunbar PR, Jakobsen BK, Sewell AK, Cerundolo V. Choi EM, et al. Among authors: dunbar pr. J Immunol. 2003 Nov 15;171(10):5116-23. doi: 10.4049/jimmunol.171.10.5116. J Immunol. 2003. PMID: 14607910
Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface.
Wooldridge L, Hutchinson SL, Choi EM, Lissina A, Jones E, Mirza F, Dunbar PR, Price DA, Cerundolo V, Sewell AK. Wooldridge L, et al. Among authors: dunbar pr. J Immunol. 2003 Dec 15;171(12):6650-60. doi: 10.4049/jimmunol.171.12.6650. J Immunol. 2003. PMID: 14662868
Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence.
Smith CL, Dunbar PR, Mirza F, Palmowski MJ, Shepherd D, Gilbert SC, Coulie P, Schneider J, Hoffman E, Hawkins R, Harris AL, Cerundolo V. Smith CL, et al. Among authors: dunbar pr. Int J Cancer. 2005 Jan 10;113(2):259-66. doi: 10.1002/ijc.20569. Int J Cancer. 2005. PMID: 15386406 Free article. Clinical Trial.
Structural and kinetic basis for heightened immunogenicity of T cell vaccines.
Chen JL, Stewart-Jones G, Bossi G, Lissin NM, Wooldridge L, Choi EM, Held G, Dunbar PR, Esnouf RM, Sami M, Boulter JM, Rizkallah P, Renner C, Sewell A, van der Merwe PA, Jakobsen BK, Griffiths G, Jones EY, Cerundolo V. Chen JL, et al. Among authors: dunbar pr. J Exp Med. 2005 Apr 18;201(8):1243-55. doi: 10.1084/jem.20042323. J Exp Med. 2005. PMID: 15837811 Free PMC article.
143 results