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High avidity antigen-specific CTL identified by CD8-independent tetramer staining.
Choi EM, Chen JL, Wooldridge L, Salio M, Lissina A, Lissin N, Hermans IF, Silk JD, Mirza F, Palmowski MJ, Dunbar PR, Jakobsen BK, Sewell AK, Cerundolo V. Choi EM, et al. Among authors: jakobsen bk. J Immunol. 2003 Nov 15;171(10):5116-23. doi: 10.4049/jimmunol.171.10.5116. J Immunol. 2003. PMID: 14607910
Structural and kinetic basis for heightened immunogenicity of T cell vaccines.
Chen JL, Stewart-Jones G, Bossi G, Lissin NM, Wooldridge L, Choi EM, Held G, Dunbar PR, Esnouf RM, Sami M, Boulter JM, Rizkallah P, Renner C, Sewell A, van der Merwe PA, Jakobsen BK, Griffiths G, Jones EY, Cerundolo V. Chen JL, et al. Among authors: jakobsen bk. J Exp Med. 2005 Apr 18;201(8):1243-55. doi: 10.1084/jem.20042323. J Exp Med. 2005. PMID: 15837811 Free PMC article.
Novel CD8+ T cell antagonists based on beta 2-microglobulin.
Glick M, Price DA, Vuidepot AL, Andersen TB, Hutchinson SL, Laugel B, Sewell AK, Boulter JM, Dunbar PR, Cerundolo V, Oxenius A, Bell JI, Richards WG, Jakobsen BK. Glick M, et al. Among authors: jakobsen bk. J Biol Chem. 2002 Jun 7;277(23):20840-6. doi: 10.1074/jbc.M201819200. Epub 2002 Mar 25. J Biol Chem. 2002. PMID: 11914379 Free article.
The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain.
Purbhoo MA, Boulter JM, Price DA, Vuidepot AL, Hourigan CS, Dunbar PR, Olson K, Dawson SJ, Phillips RE, Jakobsen BK, Bell JI, Sewell AK. Purbhoo MA, et al. Among authors: jakobsen bk. J Biol Chem. 2001 Aug 31;276(35):32786-92. doi: 10.1074/jbc.M102498200. Epub 2001 Jul 3. J Biol Chem. 2001. PMID: 11438524 Free article.
Engineering Cancer Antigen-Specific T Cells to Overcome the Immunosuppressive Effects of TGF-β.
Silk JD, Abbott RJM, Adams KJ, Bennett AD, Brett S, Cornforth TV, Crossland KL, Figueroa DJ, Jing J, O'Connor C, Pachnio A, Patasic L, Peredo CE, Quattrini A, Quinn LL, Rust AG, Saini M, Sanderson JP, Steiner D, Tavano B, Viswanathan P, Wiedermann GE, Wong R, Jakobsen BK, Britten CM, Gerry AB, Brewer JE. Silk JD, et al. Among authors: jakobsen bk. J Immunol. 2022 Jan 1;208(1):169-180. doi: 10.4049/jimmunol.2001357. Epub 2021 Dec 1. J Immunol. 2022. PMID: 34853077
Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.
Sewell AK, Gerth UC, Price DA, Purbhoo MA, Boulter JM, Gao GF, Bell JI, Phillips RE, Jakobsen BK. Sewell AK, et al. Among authors: jakobsen bk. Nat Med. 1999 Apr;5(4):399-404. doi: 10.1038/7398. Nat Med. 1999. PMID: 10202928
163 results