Lamphier M - Search Results

1

mRNA is an endogenous ligand for Toll-like receptor 3.

Karikó K, Ni H, Capodici J, Lamphier M, Weissman D. Karikó K, et al. Among authors: lamphier m. J Biol Chem. 2004 Mar 26;279(13):12542-50. doi: 10.1074/jbc.M310175200. Epub 2004 Jan 16. J Biol Chem. 2004. PMID: 14729660 Free article.

2

Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

Latz E, Verma A, Visintin A, Gong M, Sirois CM, Klein DC, Monks BG, McKnight CJ, Lamphier MS, Duprex WP, Espevik T, Golenbock DT. Latz E, et al. Among authors: lamphier ms. Nat Immunol. 2007 Jul;8(7):772-9. doi: 10.1038/ni1479. Epub 2007 Jun 17. Nat Immunol. 2007. PMID: 17572678

3

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

Parroche P, Lauw FN, Goutagny N, Latz E, Monks BG, Visintin A, Halmen KA, Lamphier M, Olivier M, Bartholomeu DC, Gazzinelli RT, Golenbock DT. Parroche P, et al. Among authors: lamphier m. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1919-24. doi: 10.1073/pnas.0608745104. Epub 2007 Jan 29. Proc Natl Acad Sci U S A. 2007. PMID: 17261807 Free PMC article.

4

Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.

Lamphier M, Zheng W, Latz E, Spyvee M, Hansen H, Rose J, Genest M, Yang H, Shaffer C, Zhao Y, Shen Y, Liu C, Liu D, Mempel TR, Rowbottom C, Chow J, Twine NC, Yu M, Gusovsky F, Ishizaka ST. Lamphier M, et al. Mol Pharmacol. 2014 Mar;85(3):429-40. doi: 10.1124/mol.113.089821. Epub 2013 Dec 16. Mol Pharmacol. 2014. PMID: 24342772

5

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes.

Tamura T, Ishihara M, Lamphier MS, Tanaka N, Oishi I, Aizawa S, Matsuyama T, Mak TW, Taki S, Taniguchi T. Tamura T, et al. Among authors: lamphier ms. Nature. 1995 Aug 17;376(6541):596-9. doi: 10.1038/376596a0. Nature. 1995. PMID: 7637809

6

Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage.

Tanaka N, Ishihara M, Lamphier MS, Nozawa H, Matsuyama T, Mak TW, Aizawa S, Tokino T, Oren M, Taniguchi T. Tanaka N, et al. Among authors: lamphier ms. Nature. 1996 Aug 29;382(6594):816-8. doi: 10.1038/382816a0. Nature. 1996. PMID: 8752276

7

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria.

Franklin BS, Ishizaka ST, Lamphier M, Gusovsky F, Hansen H, Rose J, Zheng W, Ataíde MA, de Oliveira RB, Golenbock DT, Gazzinelli RT. Franklin BS, et al. Among authors: lamphier m. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3689-94. doi: 10.1073/pnas.1015406108. Epub 2011 Feb 8. Proc Natl Acad Sci U S A. 2011. PMID: 21303985 Free PMC article.

8

TLR9 and the recognition of self and non-self nucleic acids.

Lamphier MS, Sirois CM, Verma A, Golenbock DT, Latz E. Lamphier MS, et al. Ann N Y Acad Sci. 2006 Oct;1082:31-43. doi: 10.1196/annals.1348.005. Ann N Y Acad Sci. 2006. PMID: 17145922

9

Multiple mechanisms mediate glucose repression of the yeast GAL1 gene.

Lamphier MS, Ptashne M. Lamphier MS, et al. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):5922-6. doi: 10.1073/pnas.89.13.5922. Proc Natl Acad Sci U S A. 1992. PMID: 1631075 Free PMC article.

10

A novel antagonist of the prostaglandin E(2) EP(4) receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models.

Chen Q, Muramoto K, Masaaki N, Ding Y, Yang H, Mackey M, Li W, Inoue Y, Ackermann K, Shirota H, Matsumoto I, Spyvee M, Schiller S, Sumida T, Gusovsky F, Lamphier M. Chen Q, et al. Among authors: lamphier m. Br J Pharmacol. 2010 May;160(2):292-310. doi: 10.1111/j.1476-5381.2010.00647.x. Br J Pharmacol. 2010. PMID: 20423341 Free PMC article.

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