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Targeted inhibition of p38 mitogen-activated protein kinase antagonizes cardiac injury and cell death following ischemia-reperfusion in vivo.
J Biol Chem. 2004 Apr 9;279(15):15524-30. doi: 10.1074/jbc.M313717200. Epub 2004 Jan 28.
J Biol Chem. 2004.
PMID: 14749328
Free article.
Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling.
Braz JC, Bueno OF, Liang Q, Wilkins BJ, Dai YS, Parsons S, Braunwart J, Glascock BJ, Klevitsky R, Kimball TF, Hewett TE, Molkentin JD.
Braz JC, et al. Among authors: kimball tf.
J Clin Invest. 2003 May;111(10):1475-86. doi: 10.1172/JCI17295.
J Clin Invest. 2003.
PMID: 12750397
Free PMC article.
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Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice.
Bueno OF, Wilkins BJ, Tymitz KM, Glascock BJ, Kimball TF, Lorenz JN, Molkentin JD.
Bueno OF, et al. Among authors: kimball tf.
Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4586-91. doi: 10.1073/pnas.072647999. Epub 2002 Mar 19.
Proc Natl Acad Sci U S A. 2002.
PMID: 11904392
Free PMC article.
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Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth.
Wilkins BJ, De Windt LJ, Bueno OF, Braz JC, Glascock BJ, Kimball TF, Molkentin JD.
Wilkins BJ, et al. Among authors: kimball tf.
Mol Cell Biol. 2002 Nov;22(21):7603-13. doi: 10.1128/MCB.22.21.7603-7613.2002.
Mol Cell Biol. 2002.
PMID: 12370307
Free PMC article.
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PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD.
Braz JC, et al. Among authors: kimball tf.
Nat Med. 2004 Mar;10(3):248-54. doi: 10.1038/nm1000. Epub 2004 Feb 15.
Nat Med. 2004.
PMID: 14966518
Free article.
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Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure.
Hambleton M, Hahn H, Pleger ST, Kuhn MC, Klevitsky R, Carr AN, Kimball TF, Hewett TE, Dorn GW 2nd, Koch WJ, Molkentin JD.
Hambleton M, et al. Among authors: kimball tf.
Circulation. 2006 Aug 8;114(6):574-82. doi: 10.1161/CIRCULATIONAHA.105.592550. Epub 2006 Jul 31.
Circulation. 2006.
PMID: 16880328
Free PMC article.
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Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo.
De Windt LJ, Lim HW, Bueno OF, Liang Q, Delling U, Braz JC, Glascock BJ, Kimball TF, del Monte F, Hajjar RJ, Molkentin JD.
De Windt LJ, et al. Among authors: kimball tf.
Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3322-7. doi: 10.1073/pnas.031371998.
Proc Natl Acad Sci U S A. 2001.
PMID: 11248077
Free PMC article.
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Fibroblast Growth Factor 2 Mediates Isoproterenol-induced Cardiac Hypertrophy through Activation of the Extracellular Regulated Kinase.
House SL, House BE, Glascock B, Kimball T, Nusayr E, Schultz JE, Doetschman T.
House SL, et al.
Mol Cell Pharmacol. 2010;2(4):143-154. doi: 10.4255/mcpharmacol.10.20.
Mol Cell Pharmacol. 2010.
PMID: 21274419
Free PMC article.
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