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Preclinical toxicity analyses of lentiviral vectors expressing the HIV-1 LTR-specific designer-recombinase Brec1.
Beschorner N, Künzle P, Voges M, Hauber I, Indenbirken D, Nakel J, Virdi S, Bradtke P, Lory NC, Rothe M, Paszkowski-Rogacz M, Buchholz F, Grundhoff A, Schambach A, Thirion C, Mittrücker HW, Schulze Zur Wiesch J, Hauber J, Chemnitz J. Beschorner N, et al. Among authors: hauber i. PLoS One. 2024 Mar 8;19(3):e0298542. doi: 10.1371/journal.pone.0298542. eCollection 2024. PLoS One. 2024. PMID: 38457474 Free PMC article.
In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation.
Jensen BO, Knops E, Cords L, Lübke N, Salgado M, Busman-Sahay K, Estes JD, Huyveneers LEP, Perdomo-Celis F, Wittner M, Gálvez C, Mummert C, Passaes C, Eberhard JM, Münk C, Hauber I, Hauber J, Heger E, De Clercq J, Vandekerckhove L, Bergmann S, Dunay GA, Klein F, Häussinger D, Fischer JC, Nachtkamp K, Timm J, Kaiser R, Harrer T, Luedde T, Nijhuis M, Sáez-Cirión A, Schulze Zur Wiesch J, Wensing AMJ, Martinez-Picado J, Kobbe G. Jensen BO, et al. Among authors: hauber i. Nat Med. 2023 Mar;29(3):583-587. doi: 10.1038/s41591-023-02213-x. Epub 2023 Feb 20. Nat Med. 2023. PMID: 36807684 Free PMC article.
Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues.
Gollnest T, Dinis de Oliveira T, Rath A, Hauber I, Schols D, Balzarini J, Meier C. Gollnest T, et al. Among authors: hauber i. Angew Chem Int Ed Engl. 2016 Apr 18;55(17):5255-8. doi: 10.1002/anie.201511808. Epub 2016 Mar 23. Angew Chem Int Ed Engl. 2016. PMID: 27008042
Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity.
Karpinski J, Hauber I, Chemnitz J, Schäfer C, Paszkowski-Rogacz M, Chakraborty D, Beschorner N, Hofmann-Sieber H, Lange UC, Grundhoff A, Hackmann K, Schrock E, Abi-Ghanem J, Pisabarro MT, Surendranath V, Schambach A, Lindner C, van Lunzen J, Hauber J, Buchholz F. Karpinski J, et al. Among authors: hauber i. Nat Biotechnol. 2016 Apr;34(4):401-9. doi: 10.1038/nbt.3467. Epub 2016 Feb 22. Nat Biotechnol. 2016. PMID: 26900663
Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration.
Thierry S, Benleulmi MS, Sinzelle L, Thierry E, Calmels C, Chaignepain S, Waffo-Teguo P, Merillon JM, Budke B, Pasquet JM, Litvak S, Ciuffi A, Sung P, Connell P, Hauber I, Hauber J, Andreola ML, Delelis O, Parissi V. Thierry S, et al. Among authors: hauber i. Chem Biol. 2015 Jun 18;22(6):712-23. doi: 10.1016/j.chembiol.2015.04.020. Epub 2015 Jun 4. Chem Biol. 2015. PMID: 26051216 Free PMC article.
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