Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees.
Whitehead SS, Bukreyev A, Teng MN, Firestone CY, St Claire M, Elkins WR, Collins PL, Murphy BR.
Whitehead SS, et al. Among authors: bukreyev a.
J Virol. 1999 Apr;73(4):3438-42. doi: 10.1128/JVI.73.4.3438-3442.1999.
J Virol. 1999.
PMID: 10074199
Free PMC article.
Virol. 73:466-473, 1998; A. Bukreyev et al., J. Virol. 71:8973-8982, 1997; and this study). ...The DeltaSH mutation was incorporated into a recombinant form of the cpts248/404 vaccine candidate, was evaluated for safety in seronegative chimpanzees, and can no …
Virol. 73:466-473, 1998; A. Bukreyev et al., J. Virol. 71:8973-8982, 1997; and this study). ...The DeltaSH mutation was incorp …