Alam J - Search Results

1

Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals.

Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, Huang A, Wang M, Miguel AH, Cho A, Sioutas C, Nel AE. Li N, et al. Among authors: alam j. J Immunol. 2004 Sep 1;173(5):3467-81. doi: 10.4049/jimmunol.173.5.3467. J Immunol. 2004. PMID: 15322212

2

Activation of the mouse heme oxygenase-1 gene by 15-deoxy-Delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2.

Gong P, Stewart D, Hu B, Li N, Cook J, Nel A, Alam J. Gong P, et al. Among authors: alam j. Antioxid Redox Signal. 2002 Apr;4(2):249-57. doi: 10.1089/152308602753666307. Antioxid Redox Signal. 2002. PMID: 12006176

3

Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium.

Stewart D, Killeen E, Naquin R, Alam S, Alam J. Stewart D, et al. Among authors: alam j, alam s. J Biol Chem. 2003 Jan 24;278(4):2396-402. doi: 10.1074/jbc.M209195200. Epub 2002 Nov 18. J Biol Chem. 2003. PMID: 12441344 Free article.

Nrf2 mediates inducer-dependent activation of the heme oxygenase-1 (HO-1) gene (Alam, J., Stewart, D., Touchard, C., Boinapally, S., Choi, A. M., and Cook, J. L. (1999) J. Biol. Chem. 274, 26071-26078), but the mechanism by which HO-1 inducers regulate …

Nrf2 mediates inducer-dependent activation of the heme oxygenase-1 (HO-1) gene (Alam, J., Stewart, D., Touchard, C., Boinapall …

4

Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2.

Alam J, Killeen E, Gong P, Naquin R, Hu B, Stewart D, Ingelfinger JR, Nath KA. Alam J, et al. Am J Physiol Renal Physiol. 2003 Apr;284(4):F743-52. doi: 10.1152/ajprenal.00376.2002. Epub 2002 Nov 26. Am J Physiol Renal Physiol. 2003. PMID: 12453873 Free article.

5

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element.

Balogun E, Hoque M, Gong P, Killeen E, Green CJ, Foresti R, Alam J, Motterlini R. Balogun E, et al. Among authors: alam j. Biochem J. 2003 May 1;371(Pt 3):887-95. doi: 10.1042/BJ20021619. Biochem J. 2003. PMID: 12570874 Free PMC article.

6

Phosphatidylinositol 3-kinase/Akt pathway mediates heme oxygenase-1 regulation by lipopolysaccharide.

Pischke SE, Zhou Z, Song R, Ning W, Alam J, Ryter SW, Choi AM. Pischke SE, et al. Among authors: alam j. Cell Mol Biol (Noisy-le-grand). 2005 Oct 3;51(5):461-70. Cell Mol Biol (Noisy-le-grand). 2005. PMID: 16309568

7

Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol.

Martin D, Rojo AI, Salinas M, Diaz R, Gallardo G, Alam J, De Galarreta CM, Cuadrado A. Martin D, et al. Among authors: alam j. J Biol Chem. 2004 Mar 5;279(10):8919-29. doi: 10.1074/jbc.M309660200. Epub 2003 Dec 19. J Biol Chem. 2004. PMID: 14688281 Free article.

8

Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor.

Alam J, Wicks C, Stewart D, Gong P, Touchard C, Otterbein S, Choi AM, Burow ME, Tou J. Alam J, et al. J Biol Chem. 2000 Sep 8;275(36):27694-702. doi: 10.1074/jbc.M004729200. J Biol Chem. 2000. PMID: 10874044 Free article.

9

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene.

Alam J, Stewart D, Touchard C, Boinapally S, Choi AM, Cook JL. Alam J, et al. J Biol Chem. 1999 Sep 10;274(37):26071-8. doi: 10.1074/jbc.274.37.26071. J Biol Chem. 1999. PMID: 10473555 Free article.

10

Cobalt induces heme oxygenase-1 expression by a hypoxia-inducible factor-independent mechanism in Chinese hamster ovary cells: regulation by Nrf2 and MafG transcription factors.

Gong P, Hu B, Stewart D, Ellerbe M, Figueroa YG, Blank V, Beckman BS, Alam J. Gong P, et al. Among authors: alam j. J Biol Chem. 2001 Jul 20;276(29):27018-25. doi: 10.1074/jbc.M103658200. Epub 2001 May 16. J Biol Chem. 2001. PMID: 11356853 Free article.

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