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Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: contribution of exogenous versus endogenous carcinogens.
Wallerand H, Bakkar AA, de Medina SG, Pairon JC, Yang YC, Vordos D, Bittard H, Fauconnet S, Kouyoumdjian JC, Jaurand MC, Zhang ZF, Radvanyi F, Thiery JP, Chopin DK. Wallerand H, et al. Among authors: chopin dk. Carcinogenesis. 2005 Jan;26(1):177-84. doi: 10.1093/carcin/bgh275. Epub 2004 Sep 3. Carcinogenesis. 2005. PMID: 15347601
Sensitive allele-specific PCR assay able to detect FGFR3 mutations in tumors and urine from patients with urothelial cell carcinoma of the bladder.
Bakkar AA, Quach V, Le Borgne A, Toublanc M, Henin D, Wallerand H, Radvanyi F, Bittard H, Ravery V, Gibod LB, de Medina SG, Chopin DK, Grandchamp B. Bakkar AA, et al. Among authors: chopin dk. Clin Chem. 2005 Aug;51(8):1555-7. doi: 10.1373/clinchem.2005.049619. Clin Chem. 2005. PMID: 16040860 No abstract available.
Occupational exposure to polycyclic aromatic hydrocarbons influenced neither the frequency nor the spectrum of FGFR3 mutations in bladder urothelial carcinoma.
Bakkar AA, Allory Y, Iwatsubo Y, de Medina SG, Maille P, Khreich N, Riou A, Leroy K, Vordos D, Abbou CC, Andujar P, Billebaud T, Chammings S, Conso F, De La Taille A, Fontaine E, Gattegno B, Ravery V, Sibony M, Radvanyi F, Chopin DK, Pairon JC. Bakkar AA, et al. Among authors: chopin dk. Mol Carcinog. 2010 Jan;49(1):25-31. doi: 10.1002/mc.20573. Mol Carcinog. 2010. PMID: 19722178
Gefitinib inhibits the growth and invasion of urothelial carcinoma cell lines in which Akt and MAPK activation is dependent on constitutive epidermal growth factor receptor activation.
Nicolle G, Daher A, Maillé P, Vermey M, Loric S, Bakkar A, Wallerand H, Vordos D, Vacherot F, de Medina SG, Abbou CC, Van der Kwast T, Thiery JP, Radvanyi F, Chopin DK. Nicolle G, et al. Among authors: chopin dk. Clin Cancer Res. 2006 May 1;12(9):2937-43. doi: 10.1158/1078-0432.CCR-05-2148. Clin Cancer Res. 2006. PMID: 16675591
Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors.
Billerey C, Chopin D, Aubriot-Lorton MH, Ricol D, Gil Diez de Medina S, Van Rhijn B, Bralet MP, Lefrere-Belda MA, Lahaye JB, Abbou CC, Bonaventure J, Zafrani ES, van der Kwast T, Thiery JP, Radvanyi F. Billerey C, et al. Am J Pathol. 2001 Jun;158(6):1955-9. doi: 10.1016/S0002-9440(10)64665-2. Am J Pathol. 2001. PMID: 11395371 Free PMC article.
306 results