Gibbs CS - Search Results

1

Systematic mutational analysis of cAMP-dependent protein kinase identifies unregulated catalytic subunits and defines regions important for the recognition of the regulatory subunit.

Gibbs CS, Knighton DR, Sowadski JM, Taylor SS, Zoller MJ. Gibbs CS, et al. J Biol Chem. 1992 Mar 5;267(7):4806-14. J Biol Chem. 1992. PMID: 1537860 Free article.

2

Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions.

Gibbs CS, Zoller MJ. Gibbs CS, et al. J Biol Chem. 1991 May 15;266(14):8923-31. J Biol Chem. 1991. PMID: 2026604 Free article.

3

Identification of electrostatic interactions that determine the phosphorylation site specificity of the cAMP-dependent protein kinase.

Gibbs CS, Zoller MJ. Gibbs CS, et al. Biochemistry. 1991 Jun 4;30(22):5329-34. doi: 10.1021/bi00236a001. Biochemistry. 1991. PMID: 2036400

4

A template for the protein kinase family.

Taylor SS, Knighton DR, Zheng J, Sowadski JM, Gibbs CS, Zoller MJ. Taylor SS, et al. Among authors: gibbs cs. Trends Biochem Sci. 1993 Mar;18(3):84-9. doi: 10.1016/0968-0004(93)80001-r. Trends Biochem Sci. 1993. PMID: 8480367 Review.

5

Functional requirements for inhibition of thrombin by antithrombin III in the presence and absence of heparin.

Tsiang M, Jain AK, Gibbs CS. Tsiang M, et al. Among authors: gibbs cs. J Biol Chem. 1997 May 2;272(18):12024-9. doi: 10.1074/jbc.272.18.12024. J Biol Chem. 1997. PMID: 9115268 Free article.

6

Functional mapping of the surface residues of human thrombin.

Tsiang M, Jain AK, Dunn KE, Rojas ME, Leung LL, Gibbs CS. Tsiang M, et al. Among authors: gibbs cs. J Biol Chem. 1995 Jul 14;270(28):16854-63. doi: 10.1074/jbc.270.28.16854. J Biol Chem. 1995. PMID: 7622501 Free article.

7

Selection of a suppressor mutation that restores affinity of an oligonucleotide inhibitor for thrombin using in vitro genetics.

Tsiang M, Gibbs CS, Griffin LC, Dunn KE, Leung LL. Tsiang M, et al. Among authors: gibbs cs. J Biol Chem. 1995 Aug 18;270(33):19370-6. doi: 10.1074/jbc.270.33.19370. J Biol Chem. 1995. PMID: 7642616 Free article.

8

Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery.

Carter WJ, Myles T, Gibbs CS, Leung LL, Huntington JA. Carter WJ, et al. Among authors: gibbs cs. J Biol Chem. 2004 Jun 18;279(25):26387-94. doi: 10.1074/jbc.M402364200. Epub 2004 Apr 9. J Biol Chem. 2004. PMID: 15075325 Free article.

9

Identification of critical residues on thrombin mediating its interaction with fibrin.

Hall SW, Gibbs CS, Leung LL. Hall SW, et al. Among authors: gibbs cs. Thromb Haemost. 2001 Dec;86(6):1466-74. Thromb Haemost. 2001. PMID: 11776315

10

Identification of the factor VIIa binding site on tissue factor by homologous loop swap and alanine scanning mutagenesis.

Gibbs CS, McCurdy SN, Leung LL, Paborsky LR. Gibbs CS, et al. Biochemistry. 1994 Nov 29;33(47):14003-10. doi: 10.1021/bi00251a007. Biochemistry. 1994. PMID: 7947809

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