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Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model.
Welters MJ, Filippov DV, van den Eeden SJ, Franken KL, Nouta J, Valentijn AR, van der Marel GA, Overkleeft HS, Lipford G, Offringa R, Melief CJ, van Boom JH, van der Burg SH, Drijfhout JW. Welters MJ, et al. Among authors: van boom jh, van den eeden sj, van der marel ga, van der burg sh. Vaccine. 2004 Dec 2;23(3):305-11. doi: 10.1016/j.vaccine.2004.06.008. Vaccine. 2004. PMID: 15530672
Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions.
Speetjens FM, Welters MJP, Slingerland M, van Poelgeest MIE, de Vos van Steenwijk PJ, Roozen I, Boekestijn S, Loof NM, Zom GG, Valentijn ARPM, Krebber WJ, Meeuwenoord NJ, Janssen CAH, Melief CJM, van der Marel GA, Filippov DV, van der Burg SH, Gelderblom H, Ossendorp F. Speetjens FM, et al. Among authors: van der marel ga, van poelgeest mie, van der burg sh. J Immunother Cancer. 2022 Oct;10(10):e005016. doi: 10.1136/jitc-2022-005016. J Immunother Cancer. 2022. PMID: 36261215 Free PMC article. Clinical Trial.
Linking T cell epitopes to a common linear B cell epitope: A targeting and adjuvant strategy to improve T cell responses.
Mangsbo SM, Fletcher EAK, van Maren WWC, Redeker A, Cordfunke RA, Dillmann I, Dinkelaar J, Ouchaou K, Codee JDC, van der Marel GA, Hoogerhout P, Melief CJM, Ossendorp F, Drijfhout JW. Mangsbo SM, et al. Among authors: van der marel ga, van maren wwc. Mol Immunol. 2018 Jan;93:115-124. doi: 10.1016/j.molimm.2017.11.004. Epub 2017 Nov 22. Mol Immunol. 2018. PMID: 29175591
Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes.
Biessen EA, Sliedregt-Bol K, 'T Hoen PA, Prince P, Van der Bilt E, Valentijn AR, Meeuwenoord NJ, Princen H, Bijsterbosch MK, Van der Marel GA, Van Boom JH, Van Berkel TJ. Biessen EA, et al. Among authors: van boom jh, van der marel ga, van berkel tj, van der bilt e. Bioconjug Chem. 2002 Mar-Apr;13(2):295-302. doi: 10.1021/bc015550g. Bioconjug Chem. 2002. PMID: 11906267
510 results