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An adenovirus-based HIV subtype B prime/boost vaccine regimen elicits antibodies mediating broad antibody-dependent cellular cytotoxicity against non-subtype B HIV strains.
Gómez-Román VR, Florese RH, Peng B, Montefiori DC, Kalyanaraman VS, Venzon D, Srivastava I, Barnett SW, Robert-Guroff M. Gómez-Román VR, et al. J Acquir Immune Defic Syndr. 2006 Nov 1;43(3):270-7. doi: 10.1097/01.qai.0000230318.40170.60. J Acquir Immune Defic Syndr. 2006. PMID: 16940858
Comparative evaluation of oral and intranasal priming with replication-competent adenovirus 5 host range mutant (Ad5hr)-simian immunodeficiency virus (SIV) recombinant vaccines on immunogenicity and protective efficacy against SIV(mac251).
Zhou Q, Hidajat R, Peng B, Venzon D, Aldrich MK, Richardson E, Lee EM, Kalyanaraman VS, Grimes G, Gómez-Román VR, Summers LE, Malkevich N, Robert-Guroff M. Zhou Q, et al. Among authors: gomez roman vr. Vaccine. 2007 Nov 19;25(47):8021-35. doi: 10.1016/j.vaccine.2007.09.017. Epub 2007 Sep 29. Vaccine. 2007. PMID: 17935840
Adenoviruses as vectors for HIV vaccines.
Gómez-Román VR, Robert-Guroff M. Gómez-Román VR, et al. AIDS Rev. 2003 Jul-Sep;5(3):178-85. AIDS Rev. 2003. PMID: 14598567 Review.
Replicating rather than nonreplicating adenovirus-human immunodeficiency virus recombinant vaccines are better at eliciting potent cellular immunity and priming high-titer antibodies.
Peng B, Wang LR, Gómez-Román VR, Davis-Warren A, Montefiori DC, Kalyanaraman VS, Venzon D, Zhao J, Kan E, Rowell TJ, Murthy KK, Srivastava I, Barnett SW, Robert-Guroff M. Peng B, et al. J Virol. 2005 Aug;79(16):10200-9. doi: 10.1128/JVI.79.16.10200-10209.2005. J Virol. 2005. PMID: 16051813 Free PMC article.
Improved protection of rhesus macaques against intrarectal simian immunodeficiency virus SIV(mac251) challenge by a replication-competent Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinant priming/gp120 boosting regimen.
Zhao J, Pinczewski J, Gómez-Román VR, Venzon D, Kalyanaraman VS, Markham PD, Aldrich K, Moake M, Montefiori DC, Lou Y, Pavlakis GN, Robert-Guroff M. Zhao J, et al. J Virol. 2003 Aug;77(15):8354-65. doi: 10.1128/jvi.77.15.8354-8365.2003. J Virol. 2003. PMID: 12857905 Free PMC article.
Evaluation of envelope vaccines derived from the South African subtype C human immunodeficiency virus type 1 TV1 strain.
Lian Y, Srivastava I, Gómez-Román VR, Zur Megede J, Sun Y, Kan E, Hilt S, Engelbrecht S, Himathongkham S, Luciw PA, Otten G, Ulmer JB, Donnelly JJ, Rabussay D, Montefiori D, van Rensburg EJ, Barnett SW. Lian Y, et al. Among authors: gomez roman vr. J Virol. 2005 Nov;79(21):13338-49. doi: 10.1128/JVI.79.21.13338-13349.2005. J Virol. 2005. PMID: 16227256 Free PMC article.
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