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Macrophages induce the inflammatory response in the pulmonary Arthus reaction through G alpha i2 activation that controls C5aR and Fc receptor cooperation.
Skokowa J, Ali SR, Felda O, Kumar V, Konrad S, Shushakova N, Schmidt RE, Piekorz RP, Nürnberg B, Spicher K, Birnbaumer L, Zwirner J, Claassens JW, Verbeek JS, van Rooijen N, Köhl J, Gessner JE. Skokowa J, et al. Among authors: birnbaumer l. J Immunol. 2005 Mar 1;174(5):3041-50. doi: 10.4049/jimmunol.174.5.3041. J Immunol. 2005. PMID: 15728518
B cell developmental requirement for the G alpha i2 gene.
Dalwadi H, Wei B, Schrage M, Spicher K, Su TT, Birnbaumer L, Rawlings DJ, Braun J. Dalwadi H, et al. Among authors: birnbaumer l. J Immunol. 2003 Feb 15;170(4):1707-15. doi: 10.4049/jimmunol.170.4.1707. J Immunol. 2003. PMID: 12574334
Modulation of alpha2-adrenoceptor functions by heterotrimeric Galphai protein isoforms.
Albarrán-Juárez J, Gilsbach R, Piekorz RP, Pexa K, Beetz N, Schneider J, Nürnberg B, Birnbaumer L, Hein L. Albarrán-Juárez J, et al. Among authors: birnbaumer l. J Pharmacol Exp Ther. 2009 Oct;331(1):35-44. doi: 10.1124/jpet.109.157230. Epub 2009 Jul 9. J Pharmacol Exp Ther. 2009. PMID: 19589951 Free PMC article.
Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice.
Devanathan V, Hagedorn I, Köhler D, Pexa K, Cherpokova D, Kraft P, Singh M, Rosenberger P, Stoll G, Birnbaumer L, Piekorz RP, Beer-Hammer S, Nieswandt B, Nürnberg B. Devanathan V, et al. Among authors: birnbaumer l. Proc Natl Acad Sci U S A. 2015 May 19;112(20):6491-6. doi: 10.1073/pnas.1505887112. Epub 2015 May 5. Proc Natl Acad Sci U S A. 2015. PMID: 25944935 Free PMC article.
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in macrophages by Galpha(i) proteins.
Fan H, Williams DL, Zingarelli B, Breuel KF, Teti G, Tempel GE, Spicher K, Boulay G, Birnbaumer L, Halushka PV, Cook JA. Fan H, et al. Among authors: birnbaumer l. Immunology. 2007 Sep;122(1):116-23. doi: 10.1111/j.1365-2567.2007.02619.x. Epub 2007 May 2. Immunology. 2007. PMID: 17484771 Free PMC article.
557 results