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Assessment of mercaptopurine (6MP) metabolites and 6MP metabolic key-enzymes in childhood acute lymphoblastic leukemia.
Wojtuszkiewicz A, Barcelos A, Dubbelman B, De Abreu R, Brouwer C, Bökkerink JP, de Haas V, de Groot-Kruseman H, Jansen G, Kaspers GL, Cloos J, Peters GJ. Wojtuszkiewicz A, et al. Among authors: brouwer c. Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):422-33. doi: 10.1080/15257770.2014.904519. Nucleosides Nucleotides Nucleic Acids. 2014. PMID: 24940700 Clinical Trial.
Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.
Wielinga PR, Reid G, Challa EE, van der Heijden I, van Deemter L, de Haas M, Mol C, Kuil AJ, Groeneveld E, Schuetz JD, Brouwer C, De Abreu RA, Wijnholds J, Beijnen JH, Borst P. Wielinga PR, et al. Among authors: brouwer c. Mol Pharmacol. 2002 Dec;62(6):1321-31. doi: 10.1124/mol.62.6.1321. Mol Pharmacol. 2002. PMID: 12435799
Early life exposure to vitamin D deficiency impairs molecular mechanisms that regulate liver cholesterol biosynthesis, energy metabolism, inflammation, and detoxification.
Knuth MM, Xue J, Elnagheeb M, Gharaibeh RZ, Schoenrock SA, McRitchie S, Brouwer C, Sumner SJ, Tarantino L, Valdar W, Rector RS, Simon JM, Ideraabdullah F. Knuth MM, et al. Among authors: brouwer c. Front Endocrinol (Lausanne). 2024 May 10;15:1335855. doi: 10.3389/fendo.2024.1335855. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38800476 Free PMC article.
278 results