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High cholesterol level is essential for myelin membrane growth.
Saher G, Brügger B, Lappe-Siefke C, Möbius W, Tozawa R, Wehr MC, Wieland F, Ishibashi S, Nave KA. Saher G, et al. Among authors: tozawa r. Nat Neurosci. 2005 Apr;8(4):468-75. doi: 10.1038/nn1426. Epub 2005 Mar 27. Nat Neurosci. 2005. PMID: 15793579
Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver.
Okazaki H, Tazoe F, Okazaki S, Isoo N, Tsukamoto K, Sekiya M, Yahagi N, Iizuka Y, Ohashi K, Kitamine T, Tozawa R, Inaba T, Yagyu H, Okazaki M, Shimano H, Shibata N, Arai H, Nagai RZ, Kadowaki T, Osuga J, Ishibashi S. Okazaki H, et al. Among authors: tozawa r. J Lipid Res. 2006 Sep;47(9):1950-8. doi: 10.1194/jlr.M600224-JLR200. Epub 2006 Jun 1. J Lipid Res. 2006. PMID: 16741291 Free article.
Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia.
Yagyu H, Kitamine T, Osuga J, Tozawa R, Chen Z, Kaji Y, Oka T, Perrey S, Tamura Y, Ohashi K, Okazaki H, Yahagi N, Shionoiri F, Iizuka Y, Harada K, Shimano H, Yamashita H, Gotoda T, Yamada N, Ishibashi S. Yagyu H, et al. Among authors: tozawa r. J Biol Chem. 2000 Jul 14;275(28):21324-30. doi: 10.1074/jbc.M002541200. J Biol Chem. 2000. PMID: 10777503 Free article.
Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide.
Tamura Y, Osuga J, Adachi H, Tozawa R, Takanezawa Y, Ohashi K, Yahagi N, Sekiya M, Okazaki H, Tomita S, Iizuka Y, Koizumi H, Inaba T, Yagyu H, Kamada N, Suzuki H, Shimano H, Kadowaki T, Tsujimoto M, Arai H, Yamada N, Ishibashi S. Tamura Y, et al. Among authors: tozawa r. J Biol Chem. 2004 Jul 23;279(30):30938-44. doi: 10.1074/jbc.M313088200. Epub 2004 May 15. J Biol Chem. 2004. PMID: 15145948 Free article.
Asialoglycoprotein receptor deficiency in mice lacking the major receptor subunit. Its obligate requirement for the stable expression of oligomeric receptor.
Tozawa R, Ishibashi S, Osuga J, Yamamoto K, Yagyu H, Ohashi K, Tamura Y, Yahagi N, Iizuka Y, Okazaki H, Harada K, Gotoda T, Shimano H, Kimura S, Nagai R, Yamada N. Tozawa R, et al. J Biol Chem. 2001 Apr 20;276(16):12624-8. doi: 10.1074/jbc.M011063200. Epub 2001 Jan 16. J Biol Chem. 2001. PMID: 11278827 Free article.
74 results