Perrakis A - Search Results

1

Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.

Litjens SH, Wilhelmsen K, de Pereda JM, Perrakis A, Sonnenberg A. Litjens SH, et al. Among authors: perrakis a. J Biol Chem. 2005 Jun 10;280(23):22270-7. doi: 10.1074/jbc.M411818200. Epub 2005 Apr 6. J Biol Chem. 2005. PMID: 15817481 Free article.

2

Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system.

Tong H, Hateboer G, Perrakis A, Bernards R, Sixma TK. Tong H, et al. Among authors: perrakis a. J Biol Chem. 1997 Aug 22;272(34):21381-7. doi: 10.1074/jbc.272.34.21381. J Biol Chem. 1997. PMID: 9261152 Free article.

3

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.

van Meeteren LA, Ruurs P, Christodoulou E, Goding JW, Takakusa H, Kikuchi K, Perrakis A, Nagano T, Moolenaar WH. van Meeteren LA, et al. Among authors: perrakis a. J Biol Chem. 2005 Jun 3;280(22):21155-61. doi: 10.1074/jbc.M413183200. Epub 2005 Mar 15. J Biol Chem. 2005. PMID: 15769751 Free article.

4

Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.

Ulens C, Akdemir A, Jongejan A, van Elk R, Bertrand S, Perrakis A, Leurs R, Smit AB, Sixma TK, Bertrand D, de Esch IJ. Ulens C, et al. Among authors: perrakis a. J Med Chem. 2009 Apr 23;52(8):2372-83. doi: 10.1021/jm801400g. J Med Chem. 2009. PMID: 19331415

5

The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.

Houben AJ, van Wijk XM, van Meeteren LA, van Zeijl L, van de Westerlo EM, Hausmann J, Fish A, Perrakis A, van Kuppevelt TH, Moolenaar WH. Houben AJ, et al. Among authors: perrakis a. J Biol Chem. 2013 Jan 4;288(1):510-9. doi: 10.1074/jbc.M112.358416. Epub 2012 Nov 13. J Biol Chem. 2013. PMID: 23150666 Free PMC article.

6

The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing.

Caillat C, Pefani DE, Gillespie PJ, Taraviras S, Blow JJ, Lygerou Z, Perrakis A. Caillat C, et al. Among authors: perrakis a. J Biol Chem. 2013 Nov 1;288(44):31624-34. doi: 10.1074/jbc.M113.491928. Epub 2013 Sep 24. J Biol Chem. 2013. PMID: 24064211 Free PMC article.

7

Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.

Hiruma Y, Koch A, Hazraty N, Tsakou F, Medema RH, Joosten RP, Perrakis A. Hiruma Y, et al. Among authors: perrakis a. J Biol Chem. 2017 Sep 1;292(35):14496-14504. doi: 10.1074/jbc.M117.783555. Epub 2017 Jul 18. J Biol Chem. 2017. PMID: 28726638 Free PMC article.

8

Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation.

Argenzio E, Klarenbeek J, Kedziora KM, Nahidiazar L, Isogai T, Perrakis A, Jalink K, Moolenaar WH, Innocenti M. Argenzio E, et al. Among authors: perrakis a. J Biol Chem. 2018 Dec 14;293(50):19161-19176. doi: 10.1074/jbc.RA118.002779. Epub 2018 Oct 31. J Biol Chem. 2018. PMID: 30381396 Free PMC article.

9

The domain architecture of the protozoan protein J-DNA-binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity.

Adamopoulos A, Heidebrecht T, Roosendaal J, Touw WG, Phan IQ, Beijnen J, Perrakis A. Adamopoulos A, et al. Among authors: perrakis a. J Biol Chem. 2019 Aug 23;294(34):12815-12825. doi: 10.1074/jbc.RA119.007393. Epub 2019 Jul 10. J Biol Chem. 2019. PMID: 31292194 Free PMC article.

10

Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility.

Wang W, Atherton P, Kreft M, Te Molder L, van der Poel S, Hoekman L, Celie P, Joosten RP, Fässler R, Perrakis A, Sonnenberg A. Wang W, et al. Among authors: perrakis a. J Cell Sci. 2024 May 1;137(9):jcs262116. doi: 10.1242/jcs.262116. Epub 2024 May 16. J Cell Sci. 2024. PMID: 38587458

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