Lauffenburger DA - Search Results

1

Causal protein-signaling networks derived from multiparameter single-cell data.

Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP. Sachs K, et al. Among authors: lauffenburger da. Science. 2005 Apr 22;308(5721):523-9. doi: 10.1126/science.1105809. Science. 2005. PMID: 15845847

2

Bayesian network approach to cell signaling pathway modeling.

Sachs K, Gifford D, Jaakkola T, Sorger P, Lauffenburger DA. Sachs K, et al. Among authors: lauffenburger da. Sci STKE. 2002 Sep 3;2002(148):pe38. doi: 10.1126/stke.2002.148.pe38. Sci STKE. 2002. PMID: 12209052

3

A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis.

Janes KA, Albeck JG, Peng LX, Sorger PK, Lauffenburger DA, Yaffe MB. Janes KA, et al. Among authors: lauffenburger da. Mol Cell Proteomics. 2003 Jul;2(7):463-73. doi: 10.1074/mcp.M300045-MCP200. Epub 2003 Jun 26. Mol Cell Proteomics. 2003. PMID: 12832460 Free article.

4

A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis.

Janes KA, Albeck JG, Gaudet S, Sorger PK, Lauffenburger DA, Yaffe MB. Janes KA, et al. Among authors: lauffenburger da. Science. 2005 Dec 9;310(5754):1646-53. doi: 10.1126/science.1116598. Science. 2005. PMID: 16339439

5

Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis.

Miller-Jensen K, Janes KA, Wong YL, Griffith LG, Lauffenburger DA. Miller-Jensen K, et al. Among authors: lauffenburger da. J Cell Sci. 2006 Sep 15;119(Pt 18):3788-98. doi: 10.1242/jcs.03102. Epub 2006 Aug 29. J Cell Sci. 2006. PMID: 16940353

6

EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation.

Joslin EJ, Opresko LK, Wells A, Wiley HS, Lauffenburger DA. Joslin EJ, et al. Among authors: lauffenburger da. J Cell Sci. 2007 Oct 15;120(Pt 20):3688-99. doi: 10.1242/jcs.010488. Epub 2007 Sep 25. J Cell Sci. 2007. PMID: 17895366

7

Learning signaling network structures with sparsely distributed data.

Sachs K, Itani S, Carlisle J, Nolan GP, Pe'er D, Lauffenburger DA. Sachs K, et al. Among authors: lauffenburger da. J Comput Biol. 2009 Feb;16(2):201-12. doi: 10.1089/cmb.2008.07TT. J Comput Biol. 2009. PMID: 19193145 Free PMC article.

8

Logic-based models for the analysis of cell signaling networks.

Morris MK, Saez-Rodriguez J, Sorger PK, Lauffenburger DA. Morris MK, et al. Among authors: lauffenburger da. Biochemistry. 2010 Apr 20;49(15):3216-24. doi: 10.1021/bi902202q. Biochemistry. 2010. PMID: 20225868 Free PMC article. Review.

9

Measurement and modeling of signaling at the single-cell level.

Kolitz SE, Lauffenburger DA. Kolitz SE, et al. Among authors: lauffenburger da. Biochemistry. 2012 Sep 25;51(38):7433-43. doi: 10.1021/bi300846p. Epub 2012 Sep 14. Biochemistry. 2012. PMID: 22954137 Free PMC article. Review.

10

Translating preclinical models to humans.

Brubaker DK, Lauffenburger DA. Brubaker DK, et al. Among authors: lauffenburger da. Science. 2020 Feb 14;367(6479):742-743. doi: 10.1126/science.aay8086. Science. 2020. PMID: 32054749 No abstract available.

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