Vela JE - Search Results

1

Lack of a metabolic and antiviral drug interaction between tenofovir, abacavir and lamivudine.

Ray AS, Myrick F, Vela JE, Olson LY, Eisenberg EJ, Borroto-Esodo K, Miller MD, Fridland A. Ray AS, et al. Among authors: vela je. Antivir Ther. 2005;10(3):451-7. Antivir Ther. 2005. PMID: 15918336

2

Effective metabolism and long intracellular half life of the anti-hepatitis B agent adefovir in hepatic cells.

Ray AS, Vela JE, Olson L, Fridland A. Ray AS, et al. Among authors: vela je. Biochem Pharmacol. 2004 Nov 1;68(9):1825-31. doi: 10.1016/j.bcp.2004.07.010. Biochem Pharmacol. 2004. PMID: 15450948

3

In vitro evaluation of the anti-HIV activity and metabolic interactions of tenofovir and emtricitabine.

Borroto-Esoda K, Vela JE, Myrick F, Ray AS, Miller MD. Borroto-Esoda K, et al. Among authors: vela je. Antivir Ther. 2006;11(3):377-84. Antivir Ther. 2006. PMID: 16759055

4

Simultaneous quantitation of the nucleotide analog adefovir, its phosphorylated anabolites and 2'-deoxyadenosine triphosphate by ion-pairing LC/MS/MS.

Vela JE, Olson LY, Huang A, Fridland A, Ray AS. Vela JE, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Apr 1;848(2):335-43. doi: 10.1016/j.jchromb.2006.10.063. Epub 2006 Nov 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17101307

5

Molecular assessment of the potential for renal drug interactions between tenofovir and HIV protease inhibitors.

Cihlar T, Ray AS, Laflamme G, Vela JE, Tong L, Fuller MD, Roy A, Rhodes GR. Cihlar T, et al. Among authors: vela je. Antivir Ther. 2007;12(2):267-72. Antivir Ther. 2007. PMID: 17503669

6

Effect of nucleoside and nucleotide reverse transcriptase inhibitors of HIV on endogenous nucleotide pools.

Vela JE, Miller MD, Rhodes GR, Ray AS. Vela JE, et al. Antivir Ther. 2008;13(6):789-97. Antivir Ther. 2008. PMID: 18839780

7

Mechanism of active renal tubular efflux of tenofovir.

Ray AS, Cihlar T, Robinson KL, Tong L, Vela JE, Fuller MD, Wieman LM, Eisenberg EJ, Rhodes GR. Ray AS, et al. Among authors: vela je. Antimicrob Agents Chemother. 2006 Oct;50(10):3297-304. doi: 10.1128/AAC.00251-06. Antimicrob Agents Chemother. 2006. PMID: 17005808 Free PMC article.

8

Intracellular metabolism of the nucleotide prodrug GS-9131, a potent anti-human immunodeficiency virus agent.

Ray AS, Vela JE, Boojamra CG, Zhang L, Hui H, Callebaut C, Stray K, Lin KY, Gao Y, Mackman RL, Cihlar T. Ray AS, et al. Among authors: vela je. Antimicrob Agents Chemother. 2008 Feb;52(2):648-54. doi: 10.1128/AAC.01209-07. Epub 2007 Dec 3. Antimicrob Agents Chemother. 2008. PMID: 18056281 Free PMC article.

9

Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131.

Cihlar T, Ray AS, Boojamra CG, Zhang L, Hui H, Laflamme G, Vela JE, Grant D, Chen J, Myrick F, White KL, Gao Y, Lin KY, Douglas JL, Parkin NT, Carey A, Pakdaman R, Mackman RL. Cihlar T, et al. Among authors: vela je. Antimicrob Agents Chemother. 2008 Feb;52(2):655-65. doi: 10.1128/AAC.01215-07. Epub 2007 Dec 3. Antimicrob Agents Chemother. 2008. PMID: 18056282 Free PMC article.

10

Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation.

Cihlar T, Laflamme G, Fisher R, Carey AC, Vela JE, Mackman R, Ray AS. Cihlar T, et al. Among authors: vela je. Antimicrob Agents Chemother. 2009 Jan;53(1):150-6. doi: 10.1128/AAC.01183-08. Epub 2008 Nov 10. Antimicrob Agents Chemother. 2009. PMID: 19001108 Free PMC article.

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