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Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS.
Br J Cancer. 2005 Jun 6;92(11):2032-8. doi: 10.1038/sj.bjc.6602598.
Br J Cancer. 2005.
PMID: 15928660
Free PMC article.
Linkage analysis in Dutch familial atypical multiple mole-melanoma (FAMMM) syndrome families. Effect of naevus count.
Gruis NA, Sandkuijl LA, Weber JL, van der Zee A, Borgstein AM, Bergman W, Frants RR.
Gruis NA, et al. Among authors: borgstein am.
Melanoma Res. 1993 Aug;3(4):271-7.
Melanoma Res. 1993.
PMID: 8219760
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Quantification of sequence exchange events between PMS2 and PMS2CL provides a basis for improved mutation scanning of Lynch syndrome patients.
van der Klift HM, Tops CM, Bik EC, Boogaard MW, Borgstein AM, Hansson KB, Ausems MG, Gomez Garcia E, Green A, Hes FJ, Izatt L, van Hest LP, Alonso AM, Vriends AH, Wagner A, van Zelst-Stams WA, Vasen HF, Morreau H, Devilee P, Wijnen JT.
van der Klift HM, et al. Among authors: borgstein am.
Hum Mutat. 2010 May;31(5):578-87. doi: 10.1002/humu.21229.
Hum Mutat. 2010.
PMID: 20186688
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Repair characteristics and differentiation propensity of long-term cultures of epidermal keratinocytes derived from normal and NER-deficient mice.
Backendorf C, de Wit J, van Oosten M, Stout GJ, Mitchell JR, Borgstein AM, van der Horst GT, de Gruijl FR, Brouwer J, Mullenders LH, Hoeijmakers JH.
Backendorf C, et al. Among authors: borgstein am.
DNA Repair (Amst). 2005 Nov 21;4(11):1325-36. doi: 10.1016/j.dnarep.2005.07.011. Epub 2005 Sep 22.
DNA Repair (Amst). 2005.
PMID: 16182615
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Opposite effects of Ras or PKC activation on the expression of the SPRR2A keratinocyte terminal differentiation marker.
Sark MW, Borgstein AM, Medema JP, van de Putte P, Backendorf C.
Sark MW, et al. Among authors: borgstein am.
Exp Cell Res. 1999 Aug 1;250(2):475-84. doi: 10.1006/excr.1999.4532.
Exp Cell Res. 1999.
PMID: 10413601
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Involvement of c-JUN in the regulation of terminal differentiation genes in normal and malignant keratinocytes.
Lohman FP, Gibbs S, Fischer DF, Borgstein AM, van de Putte P, Backendorf C.
Lohman FP, et al. Among authors: borgstein am.
Oncogene. 1997 Apr 3;14(13):1623-7. doi: 10.1038/sj.onc.1200974.
Oncogene. 1997.
PMID: 9129155
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