Sproul D - Search Results

1

The role of chromatin structure in regulating the expression of clustered genes.

Sproul D, Gilbert N, Bickmore WA. Sproul D, et al. Nat Rev Genet. 2005 Oct;6(10):775-81. doi: 10.1038/nrg1688. Nat Rev Genet. 2005. PMID: 16160692 Review.

2

Recruitment to the nuclear periphery can alter expression of genes in human cells.

Finlan LE, Sproul D, Thomson I, Boyle S, Kerr E, Perry P, Ylstra B, Chubb JR, Bickmore WA. Finlan LE, et al. Among authors: sproul d. PLoS Genet. 2008 Mar 21;4(3):e1000039. doi: 10.1371/journal.pgen.1000039. PLoS Genet. 2008. PMID: 18369458 Free PMC article.

3

Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination.

Eskeland R, Leeb M, Grimes GR, Kress C, Boyle S, Sproul D, Gilbert N, Fan Y, Skoultchi AI, Wutz A, Bickmore WA. Eskeland R, et al. Among authors: sproul d. Mol Cell. 2010 May 14;38(3):452-64. doi: 10.1016/j.molcel.2010.02.032. Mol Cell. 2010. PMID: 20471950 Free PMC article.

4

Analysis of active and inactive X chromosome architecture reveals the independent organization of 30 nm and large-scale chromatin structures.

Naughton C, Sproul D, Hamilton C, Gilbert N. Naughton C, et al. Among authors: sproul d. Mol Cell. 2010 Nov 12;40(3):397-409. doi: 10.1016/j.molcel.2010.10.013. Mol Cell. 2010. PMID: 21070966 Free PMC article.

5

Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression.

Latham T, Mackay L, Sproul D, Karim M, Culley J, Harrison DJ, Hayward L, Langridge-Smith P, Gilbert N, Ramsahoye BH. Latham T, et al. Among authors: sproul d. Nucleic Acids Res. 2012 Jun;40(11):4794-803. doi: 10.1093/nar/gks066. Epub 2012 Feb 9. Nucleic Acids Res. 2012. PMID: 22323521 Free PMC article.

6

Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer.

Rafique S, Thomas JS, Sproul D, Bickmore WA. Rafique S, et al. Among authors: sproul d. Genome Biol. 2015 Aug 3;16(1):145. doi: 10.1186/s13059-015-0719-9. Genome Biol. 2015. PMID: 26235388 Free PMC article.

7

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing.

Uggenti C, Lepelley A, Depp M, Badrock AP, Rodero MP, El-Daher MT, Rice GI, Dhir S, Wheeler AP, Dhir A, Albawardi W, Frémond ML, Seabra L, Doig J, Blair N, Martin-Niclos MJ, Della Mina E, Rubio-Roldán A, García-Pérez JL, Sproul D, Rehwinkel J, Hertzog J, Boland-Auge A, Olaso R, Deleuze JF, Baruteau J, Brochard K, Buckley J, Cavallera V, Cereda C, De Waele LMH, Dobbie A, Doummar D, Elmslie F, Koch-Hogrebe M, Kumar R, Lamb K, Livingston JH, Majumdar A, Lorenço CM, Orcesi S, Peudenier S, Rostasy K, Salmon CA, Scott C, Tonduti D, Touati G, Valente M, van der Linden H Jr, Van Esch H, Vermelle M, Webb K, Jackson AP, Reijns MAM, Gilbert N, Crow YJ. Uggenti C, et al. Among authors: sproul d. Nat Genet. 2020 Dec;52(12):1364-1372. doi: 10.1038/s41588-020-00737-3. Epub 2020 Nov 23. Nat Genet. 2020. PMID: 33230297 Free article.

8

Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer.

Sproul D, Nestor C, Culley J, Dickson JH, Dixon JM, Harrison DJ, Meehan RR, Sims AH, Ramsahoye BH. Sproul D, et al. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4364-9. doi: 10.1073/pnas.1013224108. Epub 2011 Feb 28. Proc Natl Acad Sci U S A. 2011. PMID: 21368160 Free PMC article.

9

Transcription factor binding predicts histone modifications in human cell lines.

Benveniste D, Sonntag HJ, Sanguinetti G, Sproul D. Benveniste D, et al. Among authors: sproul d. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13367-72. doi: 10.1073/pnas.1412081111. Epub 2014 Sep 3. Proc Natl Acad Sci U S A. 2014. PMID: 25187560 Free PMC article.

10

Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions.

Heyn P, Logan CV, Fluteau A, Challis RC, Auchynnikava T, Martin CA, Marsh JA, Taglini F, Kilanowski F, Parry DA, Cormier-Daire V, Fong CT, Gibson K, Hwa V, Ibáñez L, Robertson SP, Sebastiani G, Rappsilber J, Allshire RC, Reijns MAM, Dauber A, Sproul D, Jackson AP. Heyn P, et al. Among authors: sproul d. Nat Genet. 2019 Jan;51(1):96-105. doi: 10.1038/s41588-018-0274-x. Epub 2018 Nov 26. Nat Genet. 2019. PMID: 30478443 Free PMC article.

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