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Page 1
Cisplatin binding sites on human albumin.
Ivanov AI, Christodoulou J, Parkinson JA, Barnham KJ, Tucker A, Woodrow J, Sadler PJ. Ivanov AI, et al. Among authors: christodoulou j. J Biol Chem. 1998 Jun 12;273(24):14721-30. doi: 10.1074/jbc.273.24.14721. J Biol Chem. 1998. PMID: 9614070 Free article.
Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes.
Christodoulou J, Larsson G, Fucini P, Connell SR, Pertinhez TA, Hanson CL, Redfield C, Nierhaus KH, Robinson CV, Schleucher J, Dobson CM. Christodoulou J, et al. Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):10949-54. doi: 10.1073/pnas.0400928101. Epub 2004 Jul 19. Proc Natl Acad Sci U S A. 2004. PMID: 15263071 Free PMC article.
Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.
Chan PH, Pardon E, Menzer L, De Genst E, Kumita JR, Christodoulou J, Saerens D, Brans A, Bouillenne F, Archer DB, Robinson CV, Muyldermans S, Matagne A, Redfield C, Wyns L, Dobson CM, Dumoulin M. Chan PH, et al. Among authors: christodoulou j. Biochemistry. 2008 Oct 21;47(42):11041-54. doi: 10.1021/bi8005797. Epub 2008 Sep 25. Biochemistry. 2008. PMID: 18816062
A non-natural variant of human lysozyme (I59T) mimics the in vitro behaviour of the I56T variant that is responsible for a form of familial amyloidosis.
Hagan CL, Johnson RJ, Dhulesia A, Dumoulin M, Dumont J, De Genst E, Christodoulou J, Robinson CV, Dobson CM, Kumita JR. Hagan CL, et al. Among authors: christodoulou j. Protein Eng Des Sel. 2010 Jul;23(7):499-506. doi: 10.1093/protein/gzq023. Epub 2010 Apr 9. Protein Eng Des Sel. 2010. PMID: 20382744 Free PMC article.
A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
De Genst E, Chan PH, Pardon E, Hsu SD, Kumita JR, Christodoulou J, Menzer L, Chirgadze DY, Robinson CV, Muyldermans S, Matagne A, Wyns L, Dobson CM, Dumoulin M. De Genst E, et al. Among authors: christodoulou j. J Phys Chem B. 2013 Oct 24;117(42):13245-13258. doi: 10.1021/jp403425z. Epub 2013 Sep 24. J Phys Chem B. 2013. PMID: 23919586 Free PMC article.
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.
Porcari R, Proukakis C, Waudby CA, Bolognesi B, Mangione PP, Paton JF, Mullin S, Cabrita LD, Penco A, Relini A, Verona G, Vendruscolo M, Stoppini M, Tartaglia GG, Camilloni C, Christodoulou J, Schapira AH, Bellotti V. Porcari R, et al. Among authors: christodoulou j. J Biol Chem. 2015 Jan 23;290(4):2395-404. doi: 10.1074/jbc.M114.610527. Epub 2014 Dec 10. J Biol Chem. 2015. PMID: 25505181 Free PMC article.
569 results