Spek CA - Search Results

1

Role of coagulation FVIII in septic peritonitis assessed in hemophilic mice.

Schoenmakers SH, Brüggemann LW, Groot AP, Maijs S, Reitsma PH, Spek CA. Schoenmakers SH, et al. Among authors: spek ca. J Thromb Haemost. 2005 Dec;3(12):2738-44. doi: 10.1111/j.1538-7836.2005.01649.x. J Thromb Haemost. 2005. PMID: 16359511 Free article.

2

Two mutations in the promoter region of the human protein C gene both cause type I protein C deficiency by disruption of two HNF-3 binding sites.

Spek CA, Greengard JS, Griffin JH, Bertina RM, Reitsma PH. Spek CA, et al. J Biol Chem. 1995 Oct 13;270(41):24216-21. doi: 10.1074/jbc.270.41.24216. J Biol Chem. 1995. PMID: 7592627 Free article.

3

Genotypic variation in the promoter region of the protein C gene is associated with plasma protein C levels and thrombotic risk.

Spek CA, Koster T, Rosendaal FR, Bertina RM, Reitsma PH. Spek CA, et al. Arterioscler Thromb Vasc Biol. 1995 Feb;15(2):214-8. doi: 10.1161/01.atv.15.2.214. Arterioscler Thromb Vasc Biol. 1995. PMID: 7749828

4

Determination of the allelic and haplotype frequencies of three polymorphisms in the promoter region of the human protein C gene.

Spek CA, Poort SR, Bertina RM, Reitsma PH. Spek CA, et al. Blood Coagul Fibrinolysis. 1994 Apr;5(2):309-11. doi: 10.1097/00001721-199404000-00022. Blood Coagul Fibrinolysis. 1994. PMID: 8054464

5

Type I protein C deficiency caused by disruption of a hepatocyte nuclear factor (HNF)-6/HNF-1 binding site in the human protein C gene promoter.

Spek CA, Lannoy VJ, Lemaigre FP, Rousseau GG, Bertina RM, Reitsma PH. Spek CA, et al. J Biol Chem. 1998 Apr 24;273(17):10168-73. doi: 10.1074/jbc.273.17.10168. J Biol Chem. 1998. PMID: 9553065 Free article.

6

Identification of evolutionarily invariant sequences in the protein C gene promoter.

Spek CA, Bertina RM, Reitsma PH. Spek CA, et al. J Mol Evol. 1998 Dec;47(6):663-9. doi: 10.1007/pl00006424. J Mol Evol. 1998. PMID: 9847407

7

Unique distance- and DNA-turn-dependent interactions in the human protein C gene promoter confer submaximal transcriptional activity.

Spek CA, Bertina RM, Reitsma PH. Spek CA, et al. Biochem J. 1999 Jun 1;340 ( Pt 2)(Pt 2):513-8. Biochem J. 1999. PMID: 10333497 Free PMC article.

8

The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation.

Franco RF, de Jonge E, Dekkers PE, Timmerman JJ, Spek CA, van Deventer SJ, van Deursen P, van Kerkhoff L, van Gemen B, ten Cate H, van der Poll T, Reitsma PH. Franco RF, et al. Among authors: spek ca. Blood. 2000 Jul 15;96(2):554-9. Blood. 2000. PMID: 10887118 Free article.

9

Genetic risk factors for venous thrombosis.

Spek CA, Reitsma PH. Spek CA, et al. Mol Genet Metab. 2000 Sep-Oct;71(1-2):51-61. doi: 10.1006/mgme.2000.3051. Mol Genet Metab. 2000. PMID: 11001795 Review. No abstract available.

10

Microvascular coagulopathy and disseminated intravascular coagulation.

ten Cate H, Schoenmakers SH, Franco R, Timmerman JJ, Groot AP, Spek CA, Reitsma PH. ten Cate H, et al. Among authors: spek ca. Crit Care Med. 2001 Jul;29(7 Suppl):S95-7; discussion S97-8. doi: 10.1097/00003246-200107001-00030. Crit Care Med. 2001. PMID: 11445741 Review.

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