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Association between CYP2D6 genotype and tamoxifen-induced hot flashes in a prospective cohort.
Henry NL, Rae JM, Li L, Azzouz F, Skaar TC, Desta Z, Sikora MJ, Philips S, Nguyen AT, Storniolo AM, Hayes DF, Flockhart DA, Stearns V; Consortium on Breast Cancer Pharmacogenomics Investigators. Henry NL, et al. Among authors: flockhart da. Breast Cancer Res Treat. 2009 Oct;117(3):571-5. doi: 10.1007/s10549-009-0309-1. Epub 2009 Jan 20. Breast Cancer Res Treat. 2009. PMID: 19153830 Free PMC article. Clinical Trial.
The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen.
Goetz MP, Knox SK, Suman VJ, Rae JM, Safgren SL, Ames MM, Visscher DW, Reynolds C, Couch FJ, Lingle WL, Weinshilboum RM, Fritcher EG, Nibbe AM, Desta Z, Nguyen A, Flockhart DA, Perez EA, Ingle JN. Goetz MP, et al. Among authors: flockhart da. Breast Cancer Res Treat. 2007 Jan;101(1):113-21. doi: 10.1007/s10549-006-9428-0. Epub 2006 Nov 18. Breast Cancer Res Treat. 2007. PMID: 17115111
CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations.
Province MA, Goetz MP, Brauch H, Flockhart DA, Hebert JM, Whaley R, Suman VJ, Schroth W, Winter S, Zembutsu H, Mushiroda T, Newman WG, Lee MT, Ambrosone CB, Beckmann MW, Choi JY, Dieudonné AS, Fasching PA, Ferraldeschi R, Gong L, Haschke-Becher E, Howell A, Jordan LB, Hamann U, Kiyotani K, Krippl P, Lambrechts D, Latif A, Langsenlehner U, Lorizio W, Neven P, Nguyen AT, Park BW, Purdie CA, Quinlan P, Renner W, Schmidt M, Schwab M, Shin JG, Stingl JC, Wegman P, Wingren S, Wu AH, Ziv E, Zirpoli G, Thompson AM, Jordan VC, Nakamura Y, Altman RB, Ames MM, Weinshilboum RM, Eichelbaum M, Ingle JN, Klein TE; International Tamoxifen Pharmacogenomics Consortium. Province MA, et al. Among authors: flockhart da. Clin Pharmacol Ther. 2014 Feb;95(2):216-27. doi: 10.1038/clpt.2013.186. Epub 2013 Sep 23. Clin Pharmacol Ther. 2014. PMID: 24060820 Free PMC article.
Genetic associations with toxicity-related discontinuation of aromatase inhibitor therapy for breast cancer.
Henry NL, Skaar TC, Dantzer J, Li L, Kidwell K, Gersch C, Nguyen AT, Rae JM, Desta Z, Oesterreich S, Philips S, Carpenter JS, Storniolo AM, Stearns V, Hayes DF, Flockhart DA. Henry NL, et al. Among authors: flockhart da. Breast Cancer Res Treat. 2013 Apr;138(3):807-16. doi: 10.1007/s10549-013-2504-3. Epub 2013 Apr 2. Breast Cancer Res Treat. 2013. PMID: 23546553 Free PMC article. Clinical Trial.
Association of polymorphisms of angiogenesis genes with breast cancer.
Schneider BP, Radovich M, Sledge GW, Robarge JD, Li L, Storniolo AM, Lemler S, Nguyen AT, Hancock BA, Stout M, Skaar T, Flockhart DA. Schneider BP, et al. Among authors: flockhart da. Breast Cancer Res Treat. 2008 Sep;111(1):157-63. doi: 10.1007/s10549-007-9755-9. Epub 2007 Sep 20. Breast Cancer Res Treat. 2008. PMID: 17891484
246 results