Groot AJ - Search Results

1

Identification by phage display of single-domain antibody fragments specific for the ODD domain in hypoxia-inducible factor 1alpha.

Groot AJ, Verheesen P, Westerlaken EJ, Gort EH, van der Groep P, Bovenschen N, van der Wall E, van Diest PJ, Shvarts A. Groot AJ, et al. Lab Invest. 2006 Apr;86(4):345-56. doi: 10.1038/labinvest.3700395. Lab Invest. 2006. PMID: 16482104 Free article.

2

Llama-derived phage display antibodies in the dissection of the human disease oculopharyngeal muscular dystrophy.

van Koningsbruggen S, de Haard H, de Kievit P, Dirks RW, van Remoortere A, Groot AJ, van Engelen BG, den Dunnen JT, Verrips CT, Frants RR, van der Maarel SM. van Koningsbruggen S, et al. Among authors: groot aj. J Immunol Methods. 2003 Aug;279(1-2):149-61. doi: 10.1016/s0022-1759(03)00232-1. J Immunol Methods. 2003. PMID: 12969556

3

Hypoxia-inducible factor-1alpha expression requires PI 3-kinase activity and correlates with Akt1 phosphorylation in invasive breast carcinomas.

Gort EH, Groot AJ, Derks van de Ven TL, van der Groep P, Verlaan I, van Laar T, van Diest PJ, van der Wall E, Shvarts A. Gort EH, et al. Among authors: groot aj. Oncogene. 2006 Oct 5;25(45):6123-7. doi: 10.1038/sj.onc.1209643. Epub 2006 May 8. Oncogene. 2006. PMID: 16682946

4

Reliable and controllable antibody fragment selections from Camelid non-immune libraries for target validation.

Verheesen P, Roussis A, de Haard HJ, Groot AJ, Stam JC, den Dunnen JT, Frants RR, Verkleij AJ, Theo Verrips C, van der Maarel SM. Verheesen P, et al. Among authors: groot aj. Biochim Biophys Acta. 2006 Aug;1764(8):1307-19. doi: 10.1016/j.bbapap.2006.05.011. Epub 2006 Jun 10. Biochim Biophys Acta. 2006. PMID: 16872921

5

Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice.

van de Sluis B, Muller P, Duran K, Chen A, Groot AJ, Klomp LW, Liu PP, Wijmenga C. van de Sluis B, et al. Among authors: groot aj. Mol Cell Biol. 2007 Jun;27(11):4142-56. doi: 10.1128/MCB.01932-06. Epub 2007 Mar 19. Mol Cell Biol. 2007. PMID: 17371845 Free PMC article.

6

The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2alpha.

Gort EH, van Haaften G, Verlaan I, Groot AJ, Plasterk RH, Shvarts A, Suijkerbuijk KP, van Laar T, van der Wall E, Raman V, van Diest PJ, Tijsterman M, Vooijs M. Gort EH, et al. Among authors: groot aj. Oncogene. 2008 Mar 6;27(11):1501-10. doi: 10.1038/sj.onc.1210795. Epub 2007 Sep 17. Oncogene. 2008. PMID: 17873906

7

Functional antibodies produced by oncolytic clostridia.

Groot AJ, Mengesha A, van der Wall E, van Diest PJ, Theys J, Vooijs M. Groot AJ, et al. Biochem Biophys Res Commun. 2007 Dec 28;364(4):985-9. doi: 10.1016/j.bbrc.2007.10.126. Epub 2007 Oct 29. Biochem Biophys Res Commun. 2007. PMID: 17971292

8

Hypoxic regulation of metastasis via hypoxia-inducible factors.

Gort EH, Groot AJ, van der Wall E, van Diest PJ, Vooijs MA. Gort EH, et al. Among authors: groot aj. Curr Mol Med. 2008 Feb;8(1):60-7. doi: 10.2174/156652408783565568. Curr Mol Med. 2008. PMID: 18289014 Review.

9

HIF-1A gene mutations associated with higher microvessel density in endometrial carcinomas.

Horrée N, Groot AJ, van Hattem WA, Heintz AP, Vooijs M, van Diest PJ. Horrée N, et al. Among authors: groot aj. Histopathology. 2008 Apr;52(5):637-9. doi: 10.1111/j.1365-2559.2008.02991.x. Histopathology. 2008. PMID: 18370960 No abstract available.

10

Conditional inactivation of HIF-1 using intrabodies.

Groot AJ, Gort EH, van der Wall E, van Diest PJ, Vooijs M. Groot AJ, et al. Cell Oncol. 2008;30(5):397-409. doi: 10.3233/clo-2008-0442. Cell Oncol. 2008. PMID: 18791271 Free PMC article.

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