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Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria.
Verreck FA, de Boer T, Langenberg DM, Hoeve MA, Kramer M, Vaisberg E, Kastelein R, Kolk A, de Waal-Malefyt R, Ottenhoff TH. Verreck FA, et al. Among authors: de waal malefyt r, de boer t. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4560-5. doi: 10.1073/pnas.0400983101. Epub 2004 Mar 19. Proc Natl Acad Sci U S A. 2004. PMID: 15070757 Free PMC article.
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW. Parham C, et al. Among authors: de waal malefyt r. J Immunol. 2002 Jun 1;168(11):5699-708. doi: 10.4049/jimmunol.168.11.5699. J Immunol. 2002. PMID: 12023369
IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells.
Diveu C, McGeachy MJ, Boniface K, Stumhofer JS, Sathe M, Joyce-Shaikh B, Chen Y, Tato CM, McClanahan TK, de Waal Malefyt R, Hunter CA, Cua DJ, Kastelein RA. Diveu C, et al. Among authors: de waal malefyt r. J Immunol. 2009 May 1;182(9):5748-56. doi: 10.4049/jimmunol.0801162. J Immunol. 2009. PMID: 19380822
127 results