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Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.
Falini B, Bolli N, Shan J, Martelli MP, Liso A, Pucciarini A, Bigerna B, Pasqualucci L, Mannucci R, Rosati R, Gorello P, Diverio D, Roti G, Tiacci E, Cazzaniga G, Biondi A, Schnittger S, Haferlach T, Hiddemann W, Martelli MF, Gu W, Mecucci C, Nicoletti I. Falini B, et al. Among authors: roti g. Blood. 2006 Jun 1;107(11):4514-23. doi: 10.1182/blood-2005-11-4745. Epub 2006 Feb 2. Blood. 2006. PMID: 16455950 Free article.
Acute lymphoblastic leukaemia in Noonan syndrome.
Roti G, La Starza R, Ballanti S, Crescenzi B, Romoli S, Foá R, Tartaglia M, Aversa F, Fabrizio Martelli M, Mecucci C. Roti G, et al. Br J Haematol. 2006 May;133(4):448-50. doi: 10.1111/j.1365-2141.2006.06092.x. Br J Haematol. 2006. PMID: 16643459 Free article. No abstract available.
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia.
Falini B, Martelli MP, Bolli N, Bonasso R, Ghia E, Pallotta MT, Diverio D, Nicoletti I, Pacini R, Tabarrini A, Galletti BV, Mannucci R, Roti G, Rosati R, Specchia G, Liso A, Tiacci E, Alcalay M, Luzi L, Volorio S, Bernard L, Guarini A, Amadori S, Mandelli F, Pane F, Lo-Coco F, Saglio G, Pelicci PG, Martelli MF, Mecucci C. Falini B, et al. Among authors: roti g. Blood. 2006 Sep 15;108(6):1999-2005. doi: 10.1182/blood-2006-03-007013. Epub 2006 May 23. Blood. 2006. PMID: 16720834 Free article.
High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement.
La Starza R, Messina M, Gianfelici V, Pierini V, Matteucci C, Pierini T, Limongi MZ, Vitale A, Roti G, Chiaretti S, Foà R, Mecucci C. La Starza R, et al. Among authors: roti g. Leukemia. 2018 Aug;32(8):1807-1810. doi: 10.1038/s41375-018-0031-2. Epub 2018 Feb 2. Leukemia. 2018. PMID: 29479063 No abstract available.
64 results