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Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.
Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, Sydow K, Lau D, Szöcs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner HC, Meinertz T, Heitzer T. Baldus S, et al. Among authors: szocs k. Circulation. 2006 Apr 18;113(15):1871-8. doi: 10.1161/CIRCULATIONAHA.105.590083. Epub 2006 Apr 10. Circulation. 2006. PMID: 16606792
Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase.
Rudolph V, Rudolph TK, Schopfer FJ, Bonacci G, Lau D, Szöcs K, Klinke A, Meinertz T, Freeman BA, Baldus S. Rudolph V, et al. Among authors: szocs k. J Pharmacol Exp Ther. 2008 Nov;327(2):324-31. doi: 10.1124/jpet.108.142414. Epub 2008 Aug 13. J Pharmacol Exp Ther. 2008. PMID: 18701766 Free PMC article. Clinical Trial.
Myeloperoxidase attracts neutrophils by physical forces.
Klinke A, Nussbaum C, Kubala L, Friedrichs K, Rudolph TK, Rudolph V, Paust HJ, Schröder C, Benten D, Lau D, Szocs K, Furtmüller PG, Heeringa P, Sydow K, Duchstein HJ, Ehmke H, Schumacher U, Meinertz T, Sperandio M, Baldus S. Klinke A, et al. Among authors: szocs k. Blood. 2011 Jan 27;117(4):1350-8. doi: 10.1182/blood-2010-05-284513. Epub 2010 Oct 27. Blood. 2011. PMID: 20980678 Free article.
Myeloperoxidase upregulates endothelin receptor type B expression.
Lau D, Szöcs K, Klinke A, Rudolph T, Rudolph V, Streichert T, Blankenberg S, Baldus S. Lau D, et al. Among authors: szocs k. J Mol Cell Cardiol. 2014 Apr;69:76-82. doi: 10.1016/j.yjmcc.2013.12.007. Epub 2014 Jan 10. J Mol Cell Cardiol. 2014. PMID: 24417960
Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling.
Mollnau H, Wendt M, Szöcs K, Lassègue B, Schulz E, Oelze M, Li H, Bodenschatz M, August M, Kleschyov AL, Tsilimingas N, Walter U, Förstermann U, Meinertz T, Griendling K, Münzel T. Mollnau H, et al. Among authors: szocs k. Circ Res. 2002 Mar 8;90(4):E58-65. doi: 10.1161/01.res.0000012569.55432.02. Circ Res. 2002. PMID: 11884382
35 results