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Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase.
Feng JY, Murakami E, Zorca SM, Johnson AA, Johnson KA, Schinazi RF, Furman PA, Anderson KS. Feng JY, et al. Antimicrob Agents Chemother. 2004 Apr;48(4):1300-6. doi: 10.1128/AAC.48.4.1300-1306.2004. Antimicrob Agents Chemother. 2004. PMID: 15047533 Free PMC article.
Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance.
Das K, Bandwar RP, White KL, Feng JY, Sarafianos SG, Tuske S, Tu X, Clark AD Jr, Boyer PL, Hou X, Gaffney BL, Jones RA, Miller MD, Hughes SH, Arnold E. Das K, et al. Among authors: feng jy. J Biol Chem. 2009 Dec 11;284(50):35092-100. doi: 10.1074/jbc.M109.022525. Epub 2009 Oct 7. J Biol Chem. 2009. PMID: 19812032 Free PMC article.
470 results