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The K65R reverse transcriptase mutation in HIV-1 reverses the excision phenotype of zidovudine resistance mutations.
Antivir Ther. 2006;11(2):155-63. doi: 10.1177/135965350601100209.
Antivir Ther. 2006.
PMID: 16640096
The balance between NRTI discrimination and excision drives the susceptibility of HIV-1 RT mutants K65R, M184V and K65r+M184V.
Ly JK, Margot NA, MacArthur HL, Hung M, Miller MD, White KL.
Ly JK, et al. Among authors: macarthur hl.
Antivir Chem Chemother. 2007;18(6):307-16. doi: 10.1177/095632020701800603.
Antivir Chem Chemother. 2007.
PMID: 18320935
Free article.
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Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131.
Birkus G, Wang R, Liu X, Kutty N, MacArthur H, Cihlar T, Gibbs C, Swaminathan S, Lee W, McDermott M.
Birkus G, et al.
Antimicrob Agents Chemother. 2007 Feb;51(2):543-50. doi: 10.1128/AAC.00968-06. Epub 2006 Dec 4.
Antimicrob Agents Chemother. 2007.
PMID: 17145787
Free PMC article.
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HIV-1 integrase preassembled on donor DNA is refractory to activity stimulation by LEDGF/p75.
Yu F, Jones GS, Hung M, Wagner AH, MacArthur HL, Liu X, Leavitt S, McDermott MJ, Tsiang M.
Yu F, et al. Among authors: macarthur hl.
Biochemistry. 2007 Mar 13;46(10):2899-908. doi: 10.1021/bi602387u. Epub 2007 Feb 14.
Biochemistry. 2007.
PMID: 17298035
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Carbocyclic influenza neuraminidase inhibitors possessing a C3-cyclic amine side chain: synthesis and inhibitory activity.
Lew W, Wu H, Chen X, Graves BJ, Escarpe PA, MacArthur HL, Mendel DB, Kim CU.
Lew W, et al. Among authors: macarthur hl.
Bioorg Med Chem Lett. 2000 Jun 5;10(11):1257-60. doi: 10.1016/s0960-894x(00)00214-6.
Bioorg Med Chem Lett. 2000.
PMID: 10866394
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Bioequivalence and Relative Bioavailability Studies to Assess a New Acalabrutinib Formulation That Enables Coadministration With Proton-Pump Inhibitors.
Sharma S, Pepin X, Burri H, Zheng L, Kuptsova-Clarkson N, de Jong A, Yu T, MacArthur HL, Majewski M, Byrd JC, Furman RR, Ware JA, Mann J, Ramies D, Munugalavadla V, Sheridan L, Tomkinson H.
Sharma S, et al. Among authors: macarthur hl.
Clin Pharmacol Drug Dev. 2022 Nov;11(11):1294-1307. doi: 10.1002/cpdd.1153. Epub 2022 Aug 27.
Clin Pharmacol Drug Dev. 2022.
PMID: 36029150
Free PMC article.
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Induction of fragility at the human RNU2 locus by cytosine arabinoside is dependent upon a transcriptionally competent U2 small nuclear RNA gene and the expression of p53.
MacArthur HL, Agarwal ML, Bacchetti S.
MacArthur HL, et al.
Somat Cell Mol Genet. 1997 Nov;23(6):379-89. doi: 10.1007/BF02673748.
Somat Cell Mol Genet. 1997.
PMID: 9661701
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