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Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs.
Sullivan NJ, Geisbert TW, Geisbert JB, Shedlock DJ, Xu L, Lamoreaux L, Custers JH, Popernack PM, Yang ZY, Pau MG, Roederer M, Koup RA, Goudsmit J, Jahrling PB, Nabel GJ. Sullivan NJ, et al. Among authors: shedlock dj. PLoS Med. 2006 Jun;3(6):e177. doi: 10.1371/journal.pmed.0030177. Epub 2006 May 16. PLoS Med. 2006. PMID: 16683867 Free PMC article.
A Single Dose Respiratory Recombinant Adenovirus-Based Vaccine Provides Long-Term Protection for Non-Human Primates from Lethal Ebola Infection.
Choi JH, Jonsson-Schmunk K, Qiu X, Shedlock DJ, Strong J, Xu JX, Michie KL, Audet J, Fernando L, Myers MJ, Weiner D, Bajrovic I, Tran LQ, Wong G, Bello A, Kobinger GP, Schafer SC, Croyle MA. Choi JH, et al. Among authors: shedlock dj. Mol Pharm. 2015 Aug 3;12(8):2712-31. doi: 10.1021/mp500646d. Epub 2014 Nov 14. Mol Pharm. 2015. PMID: 25363619 Free PMC article.
Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines.
Patel A, Reuschel EL, Kraynyak KA, Racine T, Park DH, Scott VL, Audet J, Amante D, Wise MC, Keaton AA, Wong G, Villarreal DO, Walters J, Muthumani K, Shedlock DJ, de La Vega MA, Plyler R, Boyer J, Broderick KE, Yan J, Khan AS, Jones S, Bello A, Soule G, Tran KN, He S, Tierney K, Qiu X, Kobinger GP, Sardesai NY, Weiner DB. Patel A, et al. Among authors: shedlock dj. J Infect Dis. 2019 Jan 29;219(4):544-555. doi: 10.1093/infdis/jiy537. J Infect Dis. 2019. PMID: 30304515
A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates.
Mallilankaraman K, Shedlock DJ, Bao H, Kawalekar OU, Fagone P, Ramanathan AA, Ferraro B, Stabenow J, Vijayachari P, Sundaram SG, Muruganandam N, Sarangan G, Srikanth P, Khan AS, Lewis MG, Kim JJ, Sardesai NY, Muthumani K, Weiner DB. Mallilankaraman K, et al. Among authors: shedlock dj. PLoS Negl Trop Dis. 2011 Jan 11;5(1):e928. doi: 10.1371/journal.pntd.0000928. PLoS Negl Trop Dis. 2011. PMID: 21264351 Free PMC article.
A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge.
Shedlock DJ, Talbott KT, Cress C, Ferraro B, Tuyishme S, Mallilankaraman K, Cisper NJ, Morrow MP, Wu SJ, Kawalekar OU, Khan AS, Sardesai NY, Muthumani K, Shen H, Weiner DB. Shedlock DJ, et al. Vaccine. 2011 Sep 9;29(39):6755-62. doi: 10.1016/j.vaccine.2010.12.064. Epub 2011 Jan 14. Vaccine. 2011. PMID: 21238574 Free PMC article.
Chikungunya: a potentially emerging epidemic?
Thiboutot MM, Kannan S, Kawalekar OU, Shedlock DJ, Khan AS, Sarangan G, Srikanth P, Weiner DB, Muthumani K. Thiboutot MM, et al. Among authors: shedlock dj. PLoS Negl Trop Dis. 2010 Apr 27;4(4):e623. doi: 10.1371/journal.pntd.0000623. PLoS Negl Trop Dis. 2010. PMID: 20436958 Free PMC article. Review.
Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine.
Belisle SE, Yin J, Shedlock DJ, Dai A, Yan J, Hirao L, Kutzler MA, Lewis MG, Andersen H, Lank SM, Karl JA, O'Connor DH, Khan A, Sardesai N, Chang J, Aicher L, Palermo RE, Weiner DB, Katze MG, Boyer J. Belisle SE, et al. Among authors: shedlock dj. PLoS One. 2011;6(6):e19681. doi: 10.1371/journal.pone.0019681. Epub 2011 Jun 20. PLoS One. 2011. PMID: 21701683 Free PMC article.
40 results