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328 results

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A randomised trial to compare the pharmacokinetic, pharmacodynamic, and antiviral effects of peginterferon alfa-2b and peginterferon alfa-2a in patients with chronic hepatitis C (COMPARE).
Silva M, Poo J, Wagner F, Jackson M, Cutler D, Grace M, Bordens R, Cullen C, Harvey J, Laughlin M. Silva M, et al. Among authors: cullen c. J Hepatol. 2006 Aug;45(2):204-13. doi: 10.1016/j.jhep.2006.03.008. Epub 2006 Apr 18. J Hepatol. 2006. PMID: 16780997 Clinical Trial.
Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway.
Grace MJ, Lee S, Bradshaw S, Chapman J, Spond J, Cox S, Delorenzo M, Brassard D, Wylie D, Cannon-Carlson S, Cullen C, Indelicato S, Voloch M, Bordens R. Grace MJ, et al. Among authors: cullen c. J Biol Chem. 2005 Feb 25;280(8):6327-36. doi: 10.1074/jbc.M412134200. Epub 2004 Dec 13. J Biol Chem. 2005. PMID: 15596441 Free article.
Phase I trial of intravesical recombinant adenovirus mediated interferon-α2b formulated in Syn3 for Bacillus Calmette-Guérin failures in nonmuscle invasive bladder cancer.
Dinney CP, Fisher MB, Navai N, O'Donnell MA, Cutler D, Abraham A, Young S, Hutchins B, Caceres M, Kishnani N, Sode G, Cullen C, Zhang G, Grossman HB, Kamat AM, Gonzales M, Kincaid M, Ainslie N, Maneval DC, Wszolek MF, Benedict WF. Dinney CP, et al. Among authors: cullen c. J Urol. 2013 Sep;190(3):850-6. doi: 10.1016/j.juro.2013.03.030. Epub 2013 Mar 15. J Urol. 2013. PMID: 23507396 Free PMC article. Clinical Trial.
Toxicity and exposure of an adenovirus containing human interferon alpha-2b following intracystic administration in cynomolgus monkeys.
Veneziale RW, Kishnani NS, Nelson J, Resendez JC, Frank DW, Cai XY, Xie L, Cullen C, Frugone CA, Rosenfeld C, Hubbell J, Maxwell SE, Sugarman BJ, Hutchins B, Maneval D, Treinen KA. Veneziale RW, et al. Among authors: cullen c. Gene Ther. 2012 Jul;19(7):742-51. doi: 10.1038/gt.2011.116. Epub 2011 Sep 8. Gene Ther. 2012. PMID: 21900961
328 results