Obata K - Search Results

1

Pitavastatin improves cardiac function and survival in association with suppression of the myocardial endothelin system in a rat model of hypertensive heart failure.

Saka M, Obata K, Ichihara S, Cheng XW, Kimata H, Nishizawa T, Noda A, Izawa H, Nagata K, Murohara T, Yokota M. Saka M, et al. Among authors: obata k. J Cardiovasc Pharmacol. 2006 Jun;47(6):770-9. doi: 10.1097/01.fjc.0000211791.22411.0d. J Cardiovasc Pharmacol. 2006. PMID: 16810078

2

Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure.

Ichihara S, Noda A, Nagata K, Obata K, Xu J, Ichihara G, Oikawa S, Kawanishi S, Yamada Y, Yokota M. Ichihara S, et al. Among authors: obata k. Cardiovasc Res. 2006 Feb 15;69(3):726-35. doi: 10.1016/j.cardiores.2005.08.001. Epub 2005 Sep 13. Cardiovasc Res. 2006. PMID: 16165109

3

Nicorandil promotes myocardial capillary and arteriolar growth in the failing heart of Dahl salt-sensitive hypertensive rats.

Xu J, Nagata K, Obata K, Ichihara S, Izawa H, Noda A, Nagasaka T, Iwase M, Naoe T, Murohara T, Yokota M. Xu J, et al. Among authors: obata k. Hypertension. 2005 Oct;46(4):719-24. doi: 10.1161/01.HYP.0000185189.46698.15. Epub 2005 Sep 19. Hypertension. 2005. PMID: 16172417

4

Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats.

Nagata K, Obata K, Xu J, Ichihara S, Noda A, Kimata H, Kato T, Izawa H, Murohara T, Yokota M. Nagata K, et al. Among authors: obata k. Hypertension. 2006 Apr;47(4):656-64. doi: 10.1161/01.HYP.0000203772.78696.67. Epub 2006 Feb 27. Hypertension. 2006. PMID: 16505208

5

Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors.

Ichihara S, Obata K, Yamada Y, Nagata K, Noda A, Ichihara G, Yamada A, Kato T, Izawa H, Murohara T, Yokota M. Ichihara S, et al. Among authors: obata k. J Mol Cell Cardiol. 2006 Aug;41(2):318-29. doi: 10.1016/j.yjmcc.2006.05.013. Epub 2006 Jun 27. J Mol Cell Cardiol. 2006. PMID: 16806263

6

Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure.

Cheng XW, Obata K, Kuzuya M, Izawa H, Nakamura K, Asai E, Nagasaka T, Saka M, Kimata T, Noda A, Nagata K, Jin H, Shi GP, Iguchi A, Murohara T, Yokota M. Cheng XW, et al. Among authors: obata k. Hypertension. 2006 Nov;48(5):979-87. doi: 10.1161/01.HYP.0000242331.99369.2f. Epub 2006 Sep 18. Hypertension. 2006. PMID: 16982960

7

Attenuation of ventricular hypertrophy and fibrosis in rats by pitavastatin: potential role of the RhoA-extracellular signal-regulated kinase-serum response factor signalling pathway.

Saka M, Obata K, Ichihara S, Cheng XW, Kimata H, Noda A, Izawa H, Nagata K, Yokota M. Saka M, et al. Among authors: obata k. Clin Exp Pharmacol Physiol. 2006 Dec;33(12):1164-71. doi: 10.1111/j.1440-1681.2006.04508.x. Clin Exp Pharmacol Physiol. 2006. PMID: 17184496

8

Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment.

Cheng XW, Murohara T, Kuzuya M, Izawa H, Sasaki T, Obata K, Nagata K, Nishizawa T, Kobayashi M, Yamada T, Kim W, Sato K, Shi GP, Okumura K, Yokota M. Cheng XW, et al. Among authors: obata k. Am J Pathol. 2008 Aug;173(2):358-69. doi: 10.2353/ajpath.2008.071126. Epub 2008 Jun 26. Am J Pathol. 2008. PMID: 18583318 Free PMC article.

9

Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats.

Yamada T, Nagata K, Cheng XW, Obata K, Saka M, Miyachi M, Naruse K, Nishizawa T, Noda A, Izawa H, Kuzuya M, Okumura K, Murohara T, Yokota M. Yamada T, et al. Among authors: obata k. Eur J Pharmacol. 2009 Aug 1;615(1-3):163-70. doi: 10.1016/j.ejphar.2009.05.028. Epub 2009 Jun 6. Eur J Pharmacol. 2009. PMID: 19501083

10

Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers.

Cheng XW, Okumura K, Kuzuya M, Jin Z, Nagata K, Obata K, Inoue A, Hirashiki A, Takeshita K, Unno K, Harada K, Shi GP, Yokota M, Murohara T. Cheng XW, et al. Among authors: obata k. J Cardiovasc Pharmacol. 2009 Jul;54(1):47-56. doi: 10.1097/FJC.0b013e3181ab371d. J Cardiovasc Pharmacol. 2009. PMID: 19528815 Free PMC article.

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