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Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease.
Anderson JP, Walker DE, Goldstein JM, de Laat R, Banducci K, Caccavello RJ, Barbour R, Huang J, Kling K, Lee M, Diep L, Keim PS, Shen X, Chataway T, Schlossmacher MG, Seubert P, Schenk D, Sinha S, Gai WP, Chilcote TJ. Anderson JP, et al. Among authors: goldstein jm. J Biol Chem. 2006 Oct 6;281(40):29739-52. doi: 10.1074/jbc.M600933200. Epub 2006 Jul 17. J Biol Chem. 2006. PMID: 16847063 Free article.
Red blood cells are the major source of alpha-synuclein in blood.
Barbour R, Kling K, Anderson JP, Banducci K, Cole T, Diep L, Fox M, Goldstein JM, Soriano F, Seubert P, Chilcote TJ. Barbour R, et al. Among authors: goldstein jm. Neurodegener Dis. 2008;5(2):55-9. doi: 10.1159/000112832. Epub 2008 Jan 4. Neurodegener Dis. 2008. PMID: 18182779
Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system.
Inglis KJ, Chereau D, Brigham EF, Chiou SS, Schöbel S, Frigon NL, Yu M, Caccavello RJ, Nelson S, Motter R, Wright S, Chian D, Santiago P, Soriano F, Ramos C, Powell K, Goldstein JM, Babcock M, Yednock T, Bard F, Basi GS, Sham H, Chilcote TJ, McConlogue L, Griswold-Prenner I, Anderson JP. Inglis KJ, et al. Among authors: goldstein jm. J Biol Chem. 2009 Jan 30;284(5):2598-2602. doi: 10.1074/jbc.C800206200. Epub 2008 Nov 12. J Biol Chem. 2009. PMID: 19004816 Free PMC article.
Association of Lower Rostral Anterior Cingulate GABA+ and Dysregulated Cortisol Stress Response With Altered Functional Connectivity in Young Adults With Lifetime Depression: A Multimodal Imaging Investigation of Trait and State Effects.
Ironside M, Duda JM, Moser AD, Holsen LM, Zuo CS, Du F, Perlo S, Richards CE, Chen X, Nickerson LD, Null KE, Esfand SM, Alexander MM, Crowley DJ, Lauze M, Misra M, Goldstein JM, Pizzagalli DA. Ironside M, et al. Among authors: goldstein jm. Am J Psychiatry. 2024 Apr 30:appiajp20230382. doi: 10.1176/appi.ajp.20230382. Online ahead of print. Am J Psychiatry. 2024. PMID: 38685857
MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume.
Blokland GAM, Maleki N, Jovicich J, Mesholam-Gately RI, DeLisi LE, Turner JA, Shenton ME, Voineskos AN, Kahn RS, Roffman JL, Holt DJ, Ehrlich S, Kikinis Z, Dazzan P, Murray RM, Lee J, Sim K, Lam M, de Zwarte SMC, Walton E, Kelly S, Picchioni MM, Bramon E, Makris N, David AS, Mondelli V, Reinders AATS, Oykhman E, Morris DW, Gill M, Corvin AP, Cahn W, Ho N, Liu J, Gollub RL, Manoach DS, Calhoun VD, Sponheim SR, Buka SL, Cherkerzian S, Thermenos HW, Dickie EW, Ciufolini S, Reis Marques T, Crossley NA, Purcell SM, Smoller JW, van Haren NEM, Toulopoulou T, Donohoe G, Goldstein JM, Keshavan MS, Petryshen TL, Del Re EC. Blokland GAM, et al. Among authors: goldstein jm. Int J Clin Health Psychol. 2024 Apr-Jun;24(2):100458. doi: 10.1016/j.ijchp.2024.100458. Epub 2024 Apr 9. Int J Clin Health Psychol. 2024. PMID: 38623146 Free PMC article.
Effects of GABA, Sex, and Stress on Reward Learning in Current and Remitted Major Depression.
Duda JM, Moser AD, Ironside M, Null KE, Holsen LM, Zuo CS, Du F, Esfand SM, Chen X, Perlo S, Richards CE, Lobien R, Alexander M, Misra M, Goldstein JM, Pizzagalli DA. Duda JM, et al. Among authors: goldstein jm. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Feb 28:S2451-9022(24)00061-2. doi: 10.1016/j.bpsc.2024.02.009. Online ahead of print. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024. PMID: 38417785
Acute Stress Increases Striatal Connectivity With Cortical Regions Enriched for μ and κ Opioid Receptors.
Zhukovsky P, Ironside M, Duda JM, Moser AD, Null KE, Dhaynaut M, Normandin M, Guehl NJ, El Fakhri G, Alexander M, Holsen LM, Misra M, Narendran R, Hoye JM, Morris ED, Esfand SM, Goldstein JM, Pizzagalli DA. Zhukovsky P, et al. Among authors: goldstein jm. Biol Psychiatry. 2024 Feb 22:S0006-3223(24)00106-9. doi: 10.1016/j.biopsych.2024.02.005. Online ahead of print. Biol Psychiatry. 2024. PMID: 38395372
313 results