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Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease.
Anderson JP, Walker DE, Goldstein JM, de Laat R, Banducci K, Caccavello RJ, Barbour R, Huang J, Kling K, Lee M, Diep L, Keim PS, Shen X, Chataway T, Schlossmacher MG, Seubert P, Schenk D, Sinha S, Gai WP, Chilcote TJ. Anderson JP, et al. Among authors: de laat r. J Biol Chem. 2006 Oct 6;281(40):29739-52. doi: 10.1074/jbc.M600933200. Epub 2006 Jul 17. J Biol Chem. 2006. PMID: 16847063 Free article.
LINGO-1 promotes lysosomal degradation of amyloid-β protein precursor.
de Laat R, Meabon JS, Wiley JC, Hudson MP, Montine TJ, Bothwell M. de Laat R, et al. Pathobiol Aging Age Relat Dis. 2015 Mar 9;5:25796. doi: 10.3402/pba.v5.25796. eCollection 2015. Pathobiol Aging Age Relat Dis. 2015. PMID: 25758563 Free PMC article.
Developmental expression of paraoxonase 2.
Garrick JM, Dao K, de Laat R, Elsworth J, Cole TB, Marsillach J, Furlong CE, Costa LG. Garrick JM, et al. Among authors: de laat r. Chem Biol Interact. 2016 Nov 25;259(Pt B):168-174. doi: 10.1016/j.cbi.2016.04.001. Epub 2016 Apr 7. Chem Biol Interact. 2016. PMID: 27062895 Free PMC article.
Paraoxonase-2 (PON2) in brain and its potential role in neuroprotection.
Costa LG, de Laat R, Dao K, Pellacani C, Cole TB, Furlong CE. Costa LG, et al. Among authors: de laat r. Neurotoxicology. 2014 Jul;43:3-9. doi: 10.1016/j.neuro.2013.08.011. Epub 2013 Sep 4. Neurotoxicology. 2014. PMID: 24012887 Free PMC article. Review.
Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets.
Mooij P, Koopman G, Mortier D, van Heteren M, Oostermeijer H, Fagrouch Z, de Laat R, Kobinger G, Li Y, Remarque EJ, Kondova I, Verschoor EJ, Bogers WM. Mooij P, et al. Among authors: de laat r. PLoS One. 2015 May 6;10(5):e0126132. doi: 10.1371/journal.pone.0126132. eCollection 2015. PLoS One. 2015. PMID: 25946071 Free PMC article.
11 results