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MEF2 activates a genetic program promoting chamber dilation and contractile dysfunction in calcineurin-induced heart failure.
van Oort RJ, van Rooij E, Bourajjaj M, Schimmel J, Jansen MA, van der Nagel R, Doevendans PA, Schneider MD, van Echteld CJ, De Windt LJ. van Oort RJ, et al. Among authors: van rooij e, van echteld cj, van der nagel r. Circulation. 2006 Jul 25;114(4):298-308. doi: 10.1161/CIRCULATIONAHA.105.608968. Epub 2006 Jul 17. Circulation. 2006. PMID: 16847152
EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant.
van Empel VP, Bertrand AT, van Oort RJ, van der Nagel R, Engelen M, van Rijen HV, Doevendans PA, Crijns HJ, Ackerman SL, Sluiter W, De Windt LJ. van Empel VP, et al. Among authors: van rijen hv, van der nagel r, van oort rj. J Am Coll Cardiol. 2006 Aug 15;48(4):824-32. doi: 10.1016/j.jacc.2006.02.075. Epub 2006 Jul 25. J Am Coll Cardiol. 2006. PMID: 16904556 Free article.
The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy.
Damanafshan A, Elzenaar I, Samson-Couterie B, van der Made I, Bourajjaj M, van den Hoogenhof MM, van Veen HA, Picavet DI, Beqqali A, Ehler E, De Windt LJ, Pinto YM, van Oort RJ. Damanafshan A, et al. Among authors: van oort rj. Cardiovasc Res. 2018 Sep 1;114(11):1474-1486. doi: 10.1093/cvr/cvy091. Cardiovasc Res. 2018. PMID: 29648621
Role of RyR2 phosphorylation at S2814 during heart failure progression.
Respress JL, van Oort RJ, Li N, Rolim N, Dixit SS, deAlmeida A, Voigt N, Lawrence WS, Skapura DG, Skårdal K, Wisløff U, Wieland T, Ai X, Pogwizd SM, Dobrev D, Wehrens XH. Respress JL, et al. Among authors: van oort rj. Circ Res. 2012 May 25;110(11):1474-83. doi: 10.1161/CIRCRESAHA.112.268094. Epub 2012 Apr 17. Circ Res. 2012. PMID: 22511749 Free PMC article.
29 results