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Ubiquitination of MHC class I heavy chains is essential for dislocation by human cytomegalovirus-encoded US2 but not US11.
J Biol Chem. 2006 Oct 6;281(40):30063-71. doi: 10.1074/jbc.M602248200. Epub 2006 Jul 29.
J Biol Chem. 2006.
PMID: 16877758
Free article.
Human cytomegalovirus-encoded US2 and US11 target unassembled MHC class I heavy chains for degradation.
Barel MT, Hassink GC, van Voorden S, Wiertz EJ.
Barel MT, et al.
Mol Immunol. 2006 Mar;43(8):1258-66. doi: 10.1016/j.molimm.2005.07.005. Epub 2005 Aug 10.
Mol Immunol. 2006.
PMID: 16098592
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Ubiquitination is essential for human cytomegalovirus US11-mediated dislocation of MHC class I molecules from the endoplasmic reticulum to the cytosol.
Kikkert M, Hassink G, Barel M, Hirsch C, van der Wal FJ, Wiertz E.
Kikkert M, et al.
Biochem J. 2001 Sep 1;358(Pt 2):369-77. doi: 10.1042/0264-6021:3580369.
Biochem J. 2001.
PMID: 11513735
Free PMC article.
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Human cytomegalovirus-encoded US2 differentially affects surface expression of MHC class I locus products and targets membrane-bound, but not soluble HLA-G1 for degradation.
Barel MT, Ressing M, Pizzato N, van Leeuwen D, Le Bouteiller P, Lenfant F, Wiertz EJ.
Barel MT, et al.
J Immunol. 2003 Dec 15;171(12):6757-65. doi: 10.4049/jimmunol.171.12.6757.
J Immunol. 2003.
PMID: 14662880
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Subtle sequence variation among MHC class I locus products greatly influences sensitivity to HCMV US2- and US11-mediated degradation.
Barel MT, Pizzato N, Le Bouteiller P, Wiertz EJ, Lenfant F.
Barel MT, et al.
Int Immunol. 2006 Jan;18(1):173-82. doi: 10.1093/intimm/dxh362. Epub 2005 Dec 16.
Int Immunol. 2006.
PMID: 16361314
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Amino acid composition of alpha1/alpha2 domains and cytoplasmic tail of MHC class I molecules determine their susceptibility to human cytomegalovirus US11-mediated down-regulation.
Barel MT, Pizzato N, van Leeuwen D, Bouteiller PL, Wiertz EJ, Lenfant F.
Barel MT, et al.
Eur J Immunol. 2003 Jun;33(6):1707-16. doi: 10.1002/eji.200323912.
Eur J Immunol. 2003.
PMID: 12778489
Free article.
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Sequence variations in the Fanconi anaemia gene, FAC: pathogenicity of 1806insA and R548X and recognition of D195V as a polymorphic variant.
Lo ten Foe JR, Barel MT, Thuss P, Digweed M, Arwert F, Joenje H.
Lo ten Foe JR, et al. Among authors: barel mt.
Hum Genet. 1996 Nov;98(5):522-3. doi: 10.1007/s004390050252.
Hum Genet. 1996.
PMID: 8882868
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