Burke JM - Search Results

1

Computational modelling of ErbB family phosphorylation dynamics in response to transforming growth factor alpha and heregulin indicates spatial compartmentation of phosphatase activity.

Hendriks BS, Cook J, Burke JM, Beusmans JM, Lauffenburger DA, de Graaf D. Hendriks BS, et al. Among authors: burke jm. Syst Biol (Stevenage). 2006 Jan;153(1):22-33. doi: 10.1049/ip-syb:20050057. Syst Biol (Stevenage). 2006. PMID: 16983832

2

Modeling a snap-action, variable-delay switch controlling extrinsic cell death.

Albeck JG, Burke JM, Spencer SL, Lauffenburger DA, Sorger PK. Albeck JG, et al. Among authors: burke jm. PLoS Biol. 2008 Dec 2;6(12):2831-52. doi: 10.1371/journal.pbio.0060299. PLoS Biol. 2008. PMID: 19053173 Free PMC article.

3

Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks.

Kirouac DC, Saez-Rodriguez J, Swantek J, Burke JM, Lauffenburger DA, Sorger PK. Kirouac DC, et al. Among authors: burke jm. BMC Syst Biol. 2012 May 1;6:29. doi: 10.1186/1752-0509-6-29. BMC Syst Biol. 2012. PMID: 22548703 Free PMC article.

4

Physicochemical modelling of cell signalling pathways.

Aldridge BB, Burke JM, Lauffenburger DA, Sorger PK. Aldridge BB, et al. Among authors: burke jm. Nat Cell Biol. 2006 Nov;8(11):1195-203. doi: 10.1038/ncb1497. Nat Cell Biol. 2006. PMID: 17060902 Review.

5

Quantitative analysis of pathways controlling extrinsic apoptosis in single cells.

Albeck JG, Burke JM, Aldridge BB, Zhang M, Lauffenburger DA, Sorger PK. Albeck JG, et al. Among authors: burke jm. Mol Cell. 2008 Apr 11;30(1):11-25. doi: 10.1016/j.molcel.2008.02.012. Mol Cell. 2008. PMID: 18406323 Free PMC article.

6

Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation.

Jones DS, Jenney AP, Swantek JL, Burke JM, Lauffenburger DA, Sorger PK. Jones DS, et al. Among authors: burke jm. Nat Chem Biol. 2017 Jan;13(1):38-45. doi: 10.1038/nchembio.2211. Epub 2016 Oct 31. Nat Chem Biol. 2017. PMID: 27820799 Free PMC article.

7

Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease.

Madrasi K, Das R, Mohmmadabdul H, Lin L, Hyman BT, Lauffenburger DA, Albers MW, Rissman RA, Burke JM, Apgar JF, Wille L, Gruenbaum L, Hua F. Madrasi K, et al. Among authors: burke jm. Alzheimers Dement. 2021 Sep;17(9):1487-1498. doi: 10.1002/alz.12312. Epub 2021 May 2. Alzheimers Dement. 2021. PMID: 33938131 Free PMC article.

8

Virtual clinical trial simulations for a novel KRAS^G12C inhibitor (ASP2453) in non-small cell lung cancer.

Sayama H, Marcantonio D, Nagashima T, Shimazaki M, Minematsu T, Apgar JF, Burke JM, Wille L, Nagasaka Y, Kirouac DC. Sayama H, et al. Among authors: burke jm. CPT Pharmacometrics Syst Pharmacol. 2021 Aug;10(8):864-877. doi: 10.1002/psp4.12661. Epub 2021 Jun 26. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34043291 Free PMC article.

9

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.

Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Spencer SL, et al. Among authors: burke jm. Nature. 2009 May 21;459(7245):428-32. doi: 10.1038/nature08012. Epub 2009 Apr 12. Nature. 2009. PMID: 19363473 Free PMC article.

10

Quantitative Systems Pharmacology Model of a Masked, Tumor-Activated Antibody.

Stroh M, Sagert J, Burke JM, Apgar JF, Lin L, Millard BL, Michael Kavanaugh W. Stroh M, et al. Among authors: burke jm. CPT Pharmacometrics Syst Pharmacol. 2019 Sep;8(9):676-684. doi: 10.1002/psp4.12448. Epub 2019 Jul 26. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31250966 Free PMC article.

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