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A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.
Dunachie SJ, Walther M, Epstein JE, Keating S, Berthoud T, Andrews L, Andersen RF, Bejon P, Goonetilleke N, Poulton I, Webster DP, Butcher G, Watkins K, Sinden RE, Levine GL, Richie TL, Schneider J, Kaslow D, Gilbert SC, Carucci DJ, Hill AV. Dunachie SJ, et al. Among authors: hill av. Infect Immun. 2006 Oct;74(10):5933-42. doi: 10.1128/IAI.00590-06. Infect Immun. 2006. PMID: 16988273 Free PMC article. Clinical Trial.
New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1.
Goodman AL, Epp C, Moss D, Holder AA, Wilson JM, Gao GP, Long CA, Remarque EJ, Thomas AW, Ammendola V, Colloca S, Dicks MD, Biswas S, Seibel D, van Duivenvoorde LM, Gilbert SC, Hill AV, Draper SJ. Goodman AL, et al. Among authors: hill av. Infect Immun. 2010 Nov;78(11):4601-12. doi: 10.1128/IAI.00315-10. Epub 2010 Aug 16. Infect Immun. 2010. PMID: 20713623 Free PMC article.
831 results