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A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.
Dunachie SJ, Walther M, Epstein JE, Keating S, Berthoud T, Andrews L, Andersen RF, Bejon P, Goonetilleke N, Poulton I, Webster DP, Butcher G, Watkins K, Sinden RE, Levine GL, Richie TL, Schneider J, Kaslow D, Gilbert SC, Carucci DJ, Hill AV. Dunachie SJ, et al. Among authors: richie tl. Infect Immun. 2006 Oct;74(10):5933-42. doi: 10.1128/IAI.00590-06. Infect Immun. 2006. PMID: 16988273 Free PMC article. Clinical Trial.
Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine.
Wang R, Epstein J, Baraceros FM, Gorak EJ, Charoenvit Y, Carucci DJ, Hedstrom RC, Rahardjo N, Gay T, Hobart P, Stout R, Jones TR, Richie TL, Parker SE, Doolan DL, Norman J, Hoffman SL. Wang R, et al. Among authors: richie tl. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10817-22. doi: 10.1073/pnas.181123498. Epub 2001 Aug 28. Proc Natl Acad Sci U S A. 2001. PMID: 11526203 Free PMC article.
Vaccines against asexual stage malaria parasites.
Kumar S, Epstein JE, Richie TL. Kumar S, et al. Among authors: richie tl. Chem Immunol. 2002;80:262-86. doi: 10.1159/000058849. Chem Immunol. 2002. PMID: 12058644 Review. No abstract available.
Safety, tolerability, and lack of antibody responses after administration of a PfCSP DNA malaria vaccine via needle or needle-free jet injection, and comparison of intramuscular and combination intramuscular/intradermal routes.
Epstein JE, Gorak EJ, Charoenvit Y, Wang R, Freydberg N, Osinowo O, Richie TL, Stoltz EL, Trespalacios F, Nerges J, Ng J, Fallarme-Majam V, Abot E, Goh L, Parker S, Kumar S, Hedstrom RC, Norman J, Stout R, Hoffman SL. Epstein JE, et al. Among authors: richie tl. Hum Gene Ther. 2002 Sep 1;13(13):1551-60. doi: 10.1089/10430340260201644. Hum Gene Ther. 2002. PMID: 12228010
Utilization of genomic sequence information to develop malaria vaccines.
Doolan DL, Aguiar JC, Weiss WR, Sette A, Felgner PL, Regis DP, Quinones-Casas P, Yates JR 3rd, Blair PL, Richie TL, Hoffman SL, Carucci DJ. Doolan DL, et al. Among authors: richie tl. J Exp Biol. 2003 Nov;206(Pt 21):3789-802. doi: 10.1242/jeb.00615. J Exp Biol. 2003. PMID: 14506214 Review.
Safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine followed by the recombinant protein vaccine RTS,S/AS02A.
Epstein JE, Charoenvit Y, Kester KE, Wang R, Newcomer R, Fitzpatrick S, Richie TL, Tornieporth N, Heppner DG, Ockenhouse C, Majam V, Holland C, Abot E, Ganeshan H, Berzins M, Jones T, Freydberg CN, Ng J, Norman J, Carucci DJ, Cohen J, Hoffman SL. Epstein JE, et al. Among authors: richie tl. Vaccine. 2004 Apr 16;22(13-14):1592-603. doi: 10.1016/j.vaccine.2004.01.031. Vaccine. 2004. PMID: 15068840 Clinical Trial.
Induction in humans of CD8+ and CD4+ T cell and antibody responses by sequential immunization with malaria DNA and recombinant protein.
Wang R, Epstein J, Charoenvit Y, Baraceros FM, Rahardjo N, Gay T, Banania JG, Chattopadhyay R, de la Vega P, Richie TL, Tornieporth N, Doolan DL, Kester KE, Heppner DG, Norman J, Carucci DJ, Cohen JD, Hoffman SL. Wang R, et al. Among authors: richie tl. J Immunol. 2004 May 1;172(9):5561-9. doi: 10.4049/jimmunol.172.9.5561. J Immunol. 2004. PMID: 15100299
176 results