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Page 1
The pediatric preclinical testing program: description of models and early testing results.
Houghton PJ, Morton CL, Tucker C, Payne D, Favours E, Cole C, Gorlick R, Kolb EA, Zhang W, Lock R, Carol H, Tajbakhsh M, Reynolds CP, Maris JM, Courtright J, Keir ST, Friedman HS, Stopford C, Zeidner J, Wu J, Liu T, Billups CA, Khan J, Ansher S, Zhang J, Smith MA. Houghton PJ, et al. Among authors: khan j. Pediatr Blood Cancer. 2007 Dec;49(7):928-40. doi: 10.1002/pbc.21078. Pediatr Blood Cancer. 2007. PMID: 17066459
Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis.
Whiteford CC, Bilke S, Greer BT, Chen Q, Braunschweig TA, Cenacchi N, Wei JS, Smith MA, Houghton P, Morton C, Reynolds CP, Lock R, Gorlick R, Khanna C, Thiele CJ, Takikita M, Catchpoole D, Hewitt SM, Khan J. Whiteford CC, et al. Among authors: khan j. Cancer Res. 2007 Jan 1;67(1):32-40. doi: 10.1158/0008-5472.CAN-06-0610. Cancer Res. 2007. PMID: 17210681
Molecular characterization of the pediatric preclinical testing panel.
Neale G, Su X, Morton CL, Phelps D, Gorlick R, Lock RB, Reynolds CP, Maris JM, Friedman HS, Dome J, Khoury J, Triche TJ, Seeger RC, Gilbertson R, Khan J, Smith MA, Houghton PJ. Neale G, et al. Among authors: khan j. Clin Cancer Res. 2008 Jul 15;14(14):4572-83. doi: 10.1158/1078-0432.CCR-07-5090. Clin Cancer Res. 2008. PMID: 18628472 Free PMC article.
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations.
Eleveld TF, Oldridge DA, Bernard V, Koster J, Colmet Daage L, Diskin SJ, Schild L, Bentahar NB, Bellini A, Chicard M, Lapouble E, Combaret V, Legoix-Né P, Michon J, Pugh TJ, Hart LS, Rader J, Attiyeh EF, Wei JS, Zhang S, Naranjo A, Gastier-Foster JM, Hogarty MD, Asgharzadeh S, Smith MA, Guidry Auvil JM, Watkins TB, Zwijnenburg DA, Ebus ME, van Sluis P, Hakkert A, van Wezel E, van der Schoot CE, Westerhout EM, Schulte JH, Tytgat GA, Dolman ME, Janoueix-Lerosey I, Gerhard DS, Caron HN, Delattre O, Khan J, Versteeg R, Schleiermacher G, Molenaar JJ, Maris JM. Eleveld TF, et al. Among authors: khan j. Nat Genet. 2015 Aug;47(8):864-71. doi: 10.1038/ng.3333. Epub 2015 Jun 29. Nat Genet. 2015. PMID: 26121087 Free PMC article.
MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma.
Zhang S, Wei JS, Li SQ, Badgett TC, Song YK, Agarwal S, Coarfa C, Tolman C, Hurd L, Liao H, He J, Wen X, Liu Z, Thiele CJ, Westermann F, Asgharzadeh S, Seeger RC, Maris JM, Guidry Auvil JM, Smith MA, Kolaczyk ED, Shohet J, Khan J. Zhang S, et al. Among authors: khan j. Cancer Lett. 2016 Feb 28;371(2):214-24. doi: 10.1016/j.canlet.2015.11.045. Epub 2015 Dec 10. Cancer Lett. 2016. PMID: 26683771 Free PMC article.
Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.
Hingorani P, Janeway K, Crompton BD, Kadoch C, Mackall CL, Khan J, Shern JF, Schiffman J, Mirabello L, Savage SA, Ladanyi M, Meltzer P, Bult CJ, Adamson PC, Lupo PJ, Mody R, DuBois SG, Parsons DW, Khanna C, Lau C, Hawkins DS, Randall RL, Smith M, Sorensen PH, Plon SE, Skapek SX, Lessnick S, Gorlick R, Reed DR. Hingorani P, et al. Among authors: khan j. Cancer Genet. 2016 May;209(5):182-94. doi: 10.1016/j.cancergen.2016.03.004. Epub 2016 Apr 5. Cancer Genet. 2016. PMID: 27132463 Free PMC article. Review.
Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma.
Rajbhandari P, Lopez G, Capdevila C, Salvatori B, Yu J, Rodriguez-Barrueco R, Martinez D, Yarmarkovich M, Weichert-Leahey N, Abraham BJ, Alvarez MJ, Iyer A, Harenza JL, Oldridge D, De Preter K, Koster J, Asgharzadeh S, Seeger RC, Wei JS, Khan J, Vandesompele J, Mestdagh P, Versteeg R, Look AT, Young RA, Iavarone A, Lasorella A, Silva JM, Maris JM, Califano A. Rajbhandari P, et al. Among authors: khan j. Cancer Discov. 2018 May;8(5):582-599. doi: 10.1158/2159-8290.CD-16-0861. Epub 2018 Mar 6. Cancer Discov. 2018. PMID: 29510988 Free PMC article.
Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma.
Sun W, Chatterjee B, Shern JF, Patidar R, Song Y, Wang Y, Walker RL, Pawel BR, Linardic CM, Houghton P, Hewitt SM, Edelman DC, Khan J, Meltzer PS, Barr FG. Sun W, et al. Among authors: khan j. Int J Cancer. 2019 Jun 1;144(11):2707-2717. doi: 10.1002/ijc.32006. Epub 2019 Jan 15. Int J Cancer. 2019. PMID: 30565669 Free PMC article.
SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation.
Wang L, Hensch NR, Bondra K, Sreenivas P, Zhao XR, Chen J, Moreno Campos R, Baxi K, Vaseva AV, Sunkel BD, Gryder BE, Pomella S, Stanton BZ, Zheng S, Chen EY, Rota R, Khan J, Houghton PJ, Ignatius MS. Wang L, et al. Among authors: khan j. Cancer Res. 2021 Nov 1;81(21):5451-5463. doi: 10.1158/0008-5472.CAN-20-4191. Epub 2021 Aug 30. Cancer Res. 2021. PMID: 34462275 Free PMC article.
2,957 results